Fibromyalgia and Fatigue: Central Processing, Widespread Dysfunction

Patrick H. Finan; Alex J. Zautra

doi:10.1016/j.pmrj.2010.03.021

Fibromyalgia and Fatigue: Central Processing, Widespread Dysfunction

Patrick H. Finan, Alex J. Zautra

Psychology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Abstract: Biological and psychological bases for the covariation of pain and fatigue in fibromyalgia (FM) are reviewed. FM is characterized as a disorder of central sensitization, with pain and fatigue as the most prominent symptoms. The roles of sleep disturbance and affective dysregulation as both precipitants and consequences of pain and fatigue in FM are discussed. It is argued that a positive affective disturbance may uniquely characterize pain and fatigue symptoms in FM. Finally, pharmacological and nonpharmacological treatments for FM are highlighted, with an emphasis on the efficacy of these treatments in alleviating pain and fatigue symptoms.

Original language	English (US)
Pages (from-to)	431-437
Number of pages	7
Journal	PM and R
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/j.pmrj.2010.03.021
State	Published - May 2010

ASJC Scopus subject areas

Physical Therapy, Sports Therapy and Rehabilitation
Rehabilitation
Neurology
Clinical Neurology

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abstract = "Abstract: Biological and psychological bases for the covariation of pain and fatigue in fibromyalgia (FM) are reviewed. FM is characterized as a disorder of central sensitization, with pain and fatigue as the most prominent symptoms. The roles of sleep disturbance and affective dysregulation as both precipitants and consequences of pain and fatigue in FM are discussed. It is argued that a positive affective disturbance may uniquely characterize pain and fatigue symptoms in FM. Finally, pharmacological and nonpharmacological treatments for FM are highlighted, with an emphasis on the efficacy of these treatments in alleviating pain and fatigue symptoms.",

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AB - Abstract: Biological and psychological bases for the covariation of pain and fatigue in fibromyalgia (FM) are reviewed. FM is characterized as a disorder of central sensitization, with pain and fatigue as the most prominent symptoms. The roles of sleep disturbance and affective dysregulation as both precipitants and consequences of pain and fatigue in FM are discussed. It is argued that a positive affective disturbance may uniquely characterize pain and fatigue symptoms in FM. Finally, pharmacological and nonpharmacological treatments for FM are highlighted, with an emphasis on the efficacy of these treatments in alleviating pain and fatigue symptoms.

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Fibromyalgia and Fatigue: Central Processing, Widespread Dysfunction

Abstract

ASJC Scopus subject areas

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