Fibrinogen adsorption onto microwave plasma chemical vapor deposited diamond films

J. M. Garguilo, B. A. Davis, M. Buddie, F. A M Köck, Robert Nemanich

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

This study investigates the haemocompatibility of diamond films and attempts to correlate the results to structural characteristics and surface termination. The samples evaluated consisted of polycrystalline and nanocrystalline diamond films, single crystal diamond, titanium and silicon. Raman spectroscopy detailed the sp3 and sp2 bonding configurations while surface morphology was imaged using atomic force microscopy. Initial contact angles of deionized water were obtained using the sessile drop method. Samples exposed to a hydrogen plasma, and thus hydrogen terminated, became more hydrophobic while samples oxidized by a nitric acid etch became more hydrophilic. The adsorption process of the human protein fibrinogen was then studied on each of the samples. The water contact angle for the MPCVD and single crystal diamond samples did not change, indicating little protein adsorption. Titanium and silicon samples became more hydrophilic as a result of adhered fibrinogen protein.

Original languageEnglish (US)
Pages (from-to)595-599
Number of pages5
JournalDiamond and Related Materials
Volume13
Issue number4-8
DOIs
StatePublished - Apr 2004
Externally publishedYes

Fingerprint

fibrinogen
Diamond films
diamond films
Fibrinogen
Diamond
Vapors
Microwaves
Silicon
vapors
Titanium
Proteins
Plasmas
Adsorption
microwaves
Contact angle
adsorption
Hydrogen
Diamonds
Single crystals
Nitric Acid

Keywords

  • Biocompatibility
  • Diamond
  • Diamond properties and applications
  • MPCVD

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces

Cite this

Fibrinogen adsorption onto microwave plasma chemical vapor deposited diamond films. / Garguilo, J. M.; Davis, B. A.; Buddie, M.; Köck, F. A M; Nemanich, Robert.

In: Diamond and Related Materials, Vol. 13, No. 4-8, 04.2004, p. 595-599.

Research output: Contribution to journalArticle

Garguilo, J. M. ; Davis, B. A. ; Buddie, M. ; Köck, F. A M ; Nemanich, Robert. / Fibrinogen adsorption onto microwave plasma chemical vapor deposited diamond films. In: Diamond and Related Materials. 2004 ; Vol. 13, No. 4-8. pp. 595-599.
@article{1df4a22855b645fa86bd6636cf5f9cb4,
title = "Fibrinogen adsorption onto microwave plasma chemical vapor deposited diamond films",
abstract = "This study investigates the haemocompatibility of diamond films and attempts to correlate the results to structural characteristics and surface termination. The samples evaluated consisted of polycrystalline and nanocrystalline diamond films, single crystal diamond, titanium and silicon. Raman spectroscopy detailed the sp3 and sp2 bonding configurations while surface morphology was imaged using atomic force microscopy. Initial contact angles of deionized water were obtained using the sessile drop method. Samples exposed to a hydrogen plasma, and thus hydrogen terminated, became more hydrophobic while samples oxidized by a nitric acid etch became more hydrophilic. The adsorption process of the human protein fibrinogen was then studied on each of the samples. The water contact angle for the MPCVD and single crystal diamond samples did not change, indicating little protein adsorption. Titanium and silicon samples became more hydrophilic as a result of adhered fibrinogen protein.",
keywords = "Biocompatibility, Diamond, Diamond properties and applications, MPCVD",
author = "Garguilo, {J. M.} and Davis, {B. A.} and M. Buddie and K{\"o}ck, {F. A M} and Robert Nemanich",
year = "2004",
month = "4",
doi = "10.1016/j.diamond.2003.10.008",
language = "English (US)",
volume = "13",
pages = "595--599",
journal = "Diamond and Related Materials",
issn = "0925-9635",
publisher = "Elsevier BV",
number = "4-8",

}

TY - JOUR

T1 - Fibrinogen adsorption onto microwave plasma chemical vapor deposited diamond films

AU - Garguilo, J. M.

AU - Davis, B. A.

AU - Buddie, M.

AU - Köck, F. A M

AU - Nemanich, Robert

PY - 2004/4

Y1 - 2004/4

N2 - This study investigates the haemocompatibility of diamond films and attempts to correlate the results to structural characteristics and surface termination. The samples evaluated consisted of polycrystalline and nanocrystalline diamond films, single crystal diamond, titanium and silicon. Raman spectroscopy detailed the sp3 and sp2 bonding configurations while surface morphology was imaged using atomic force microscopy. Initial contact angles of deionized water were obtained using the sessile drop method. Samples exposed to a hydrogen plasma, and thus hydrogen terminated, became more hydrophobic while samples oxidized by a nitric acid etch became more hydrophilic. The adsorption process of the human protein fibrinogen was then studied on each of the samples. The water contact angle for the MPCVD and single crystal diamond samples did not change, indicating little protein adsorption. Titanium and silicon samples became more hydrophilic as a result of adhered fibrinogen protein.

AB - This study investigates the haemocompatibility of diamond films and attempts to correlate the results to structural characteristics and surface termination. The samples evaluated consisted of polycrystalline and nanocrystalline diamond films, single crystal diamond, titanium and silicon. Raman spectroscopy detailed the sp3 and sp2 bonding configurations while surface morphology was imaged using atomic force microscopy. Initial contact angles of deionized water were obtained using the sessile drop method. Samples exposed to a hydrogen plasma, and thus hydrogen terminated, became more hydrophobic while samples oxidized by a nitric acid etch became more hydrophilic. The adsorption process of the human protein fibrinogen was then studied on each of the samples. The water contact angle for the MPCVD and single crystal diamond samples did not change, indicating little protein adsorption. Titanium and silicon samples became more hydrophilic as a result of adhered fibrinogen protein.

KW - Biocompatibility

KW - Diamond

KW - Diamond properties and applications

KW - MPCVD

UR - http://www.scopus.com/inward/record.url?scp=2442617101&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2442617101&partnerID=8YFLogxK

U2 - 10.1016/j.diamond.2003.10.008

DO - 10.1016/j.diamond.2003.10.008

M3 - Article

AN - SCOPUS:2442617101

VL - 13

SP - 595

EP - 599

JO - Diamond and Related Materials

JF - Diamond and Related Materials

SN - 0925-9635

IS - 4-8

ER -