Abstract
The fast separation of long DNA via electrodeless dielectrophoresis in a simple and easy-to-fabricate microfluidic device is presented. An AC voltage is applied to an array of periodically arranged posts creating dielectrophoretic traps. Size-dependent migration velocities are obtained by applying an additional DC voltage, which drives the DNA through the structured microchannel. With this technique we are able to achieve fast and efficient separations of λ- and T2-DNA. The mechanism is analysed in terms of a Kramer's rate and a notable change in the diffusion coefficient of λ -DNA is observed.
Original language | English (US) |
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Title of host publication | Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | Japan Academic Association Inc |
Pages | 383-385 |
Number of pages | 3 |
State | Published - 2006 |
Externally published | Yes |
Event | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: Nov 5 2006 → Nov 9 2006 |
Other
Other | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 |
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Country/Territory | Japan |
City | Tokyo |
Period | 11/5/06 → 11/9/06 |
Keywords
- Dielectrophoresis
- DNA
- Microfluidics
- Separation
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering