Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Raimond L. Winslow, Dongming Cai, Ying-Cheng Lai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

Original languageEnglish (US)
Title of host publicationProceedings of the ACM/IEEE Supercomputing Conference
Editors Anon
PublisherIEEE
Pages560-569
Number of pages10
StatePublished - 1994
Externally publishedYes
EventProceedings of the 1994 Supercomputing Conference - Washington, DC, USA
Duration: Nov 14 1994Nov 18 1994

Other

OtherProceedings of the 1994 Supercomputing Conference
CityWashington, DC, USA
Period11/14/9411/18/94

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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