Evolution of obesity in a low birth weight cohort

P. H. Casey, Robert Bradley, L. Whiteside-Mansell, K. Barrett, J. M. Gossett, P. M. Simpson

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Objective:The objective of this study was to determine the evolution of obesity status (OS) in a longitudinal cohort of low birth weight preterm (LBWPT) infants to an age of 8 years, and to determine whether rapid weight gain in the first year of life independently predicts 8-year OS. Study Design:In total, 985 infants (birth weight ≤ 2500 g, gestation age ≤ 37 weeks) were recruited from the nursery in an eight-site intervention research program and were evaluated at an age of 3, 5, 6.5 and 8 years. Weight and height were measured by standard protocol at each visit and body mass index was calculated. Obesity status is ≥95% for age and sex. Multiple logistic analyses were performed on 8-year OS with predictor variables including infant race, gender, small for gestational age status, birth weight category, neonatal health index, treatment group and first-year weight gain; maternal education and weight status before conception; and HOME Inventory. Result:Overall, 2.3% were OS at an age of 3 years, 6.1% at an age of 5 years, 7.7% at age 6.5 years and 8.7% at an age 8 years. OS varied by birth weight category at each visit. The infants born ≤ 1500 g had the lowest prevalence of OS at each age. In the logistic regression, maternal race (Hispanic) (adjusted odds ratio = 2.8, confidence interval = 1.2 to 6.8), maternal obese status (adjusted odds ratio 3.4, confidence interval = 1.5 to 7.8) and first-year weight gain (adjusted odds ratio = 2.7, confidence interval = 1.9 to 3.9), significantly predicted 8-year OS. Conclusion:OS is common in LBWPT infants during childhood, and prevalence varies by birth weight category. High weight gain in the first year of life is an important predictor of the development of OS in LBWPT children.

Original languageEnglish (US)
Pages (from-to)91-96
Number of pages6
JournalJournal of Perinatology
Volume32
Issue number2
DOIs
StatePublished - Feb 2012

Fingerprint

Low Birth Weight Infant
Obesity
Birth Weight
Weight Gain
Odds Ratio
Mothers
Confidence Intervals
Premature Infants
Weights and Measures
Nurseries
Hispanic Americans
Gestational Age
Body Mass Index
Logistic Models
Education
Equipment and Supplies
Pregnancy

Keywords

  • childhood obesity
  • low birth weight
  • obese children

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Casey, P. H., Bradley, R., Whiteside-Mansell, L., Barrett, K., Gossett, J. M., & Simpson, P. M. (2012). Evolution of obesity in a low birth weight cohort. Journal of Perinatology, 32(2), 91-96. https://doi.org/10.1038/jp.2011.75

Evolution of obesity in a low birth weight cohort. / Casey, P. H.; Bradley, Robert; Whiteside-Mansell, L.; Barrett, K.; Gossett, J. M.; Simpson, P. M.

In: Journal of Perinatology, Vol. 32, No. 2, 02.2012, p. 91-96.

Research output: Contribution to journalArticle

Casey, PH, Bradley, R, Whiteside-Mansell, L, Barrett, K, Gossett, JM & Simpson, PM 2012, 'Evolution of obesity in a low birth weight cohort', Journal of Perinatology, vol. 32, no. 2, pp. 91-96. https://doi.org/10.1038/jp.2011.75
Casey PH, Bradley R, Whiteside-Mansell L, Barrett K, Gossett JM, Simpson PM. Evolution of obesity in a low birth weight cohort. Journal of Perinatology. 2012 Feb;32(2):91-96. https://doi.org/10.1038/jp.2011.75
Casey, P. H. ; Bradley, Robert ; Whiteside-Mansell, L. ; Barrett, K. ; Gossett, J. M. ; Simpson, P. M. / Evolution of obesity in a low birth weight cohort. In: Journal of Perinatology. 2012 ; Vol. 32, No. 2. pp. 91-96.
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