Evo-devo models of tooth development and the origin of hominoid molar diversity

Alejandra Ortiz, Shara E. Bailey, Gary Schwartz, Jean Jacques Hublin, Matthew M. Skinner

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The detailed anatomical features that characterize fossil hominin molars figure prominently in the reconstruction of their taxonomy, phylogeny, and paleobiology. Despite the prominence of molar form in human origins research, the underlying developmental mechanisms generating the diversity of tooth crown features remain poorly understood. A model of tooth morphogenesis-the patterning cascade model (PCM)-provides a developmental framework to explore how and why the varying molar morphologies arose throughout human evolution. We generated virtual maps of the inner enamel epithelium-an indelibly preserved record of enamel knot arrangement-in 17 living and fossil hominoid species to investigate whether the PCM explains the expression of all major accessory cusps. We found that most of the variation and evolutionary changes in hominoid molar morphology followed the general developmental rule shared by all mammals, outlined by the PCM. Our results have implications for the accurate interpretation of molar crown configuration in hominoid systematics.

Original languageEnglish (US)
Article numbereaar2334
JournalScience advances
Volume4
Issue number4
DOIs
StatePublished - Apr 11 2018

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Fossils
Dental Enamel
Tooth
Tooth Crown
Hominidae
Phylogeny
Crowns
Morphogenesis
Mammals
Epithelium
Research

ASJC Scopus subject areas

  • General

Cite this

Evo-devo models of tooth development and the origin of hominoid molar diversity. / Ortiz, Alejandra; Bailey, Shara E.; Schwartz, Gary; Hublin, Jean Jacques; Skinner, Matthew M.

In: Science advances, Vol. 4, No. 4, eaar2334, 11.04.2018.

Research output: Contribution to journalArticle

Ortiz, Alejandra ; Bailey, Shara E. ; Schwartz, Gary ; Hublin, Jean Jacques ; Skinner, Matthew M. / Evo-devo models of tooth development and the origin of hominoid molar diversity. In: Science advances. 2018 ; Vol. 4, No. 4.
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