Abstract
HLA data from the A and B loci for 22 populations were compared with the neutrality expectations from Ewens' sampling theory. In 25 of 44 cases, there was significantly less homozygosity than expected. Although a number of factors can affect homozygosity in this manner, upon close examination only symmetrical balancing selection appears to be consistent with these data.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 449-456 |
| Number of pages | 8 |
| Journal | Genetics |
| Volume | 104 |
| Issue number | 3 |
| State | Published - 1983 |
ASJC Scopus subject areas
- Genetics