Abstract
HLA data from the A and B loci for 22 populations were compared with the neutrality expectations from Ewens' sampling theory. In 25 of 44 cases, there was significantly less homozygosity than expected. Although a number of factors can affect homozygosity in this manner, upon close examination only symmetrical balancing selection appears to be consistent with these data.
Original language | English (US) |
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Pages (from-to) | 449-456 |
Number of pages | 8 |
Journal | Genetics |
Volume | 104 |
Issue number | 3 |
State | Published - 1983 |
ASJC Scopus subject areas
- Genetics