Eusocial insects as emerging models for behavioural epigenetics

Hua Yan, Daniel F. Simola, Roberto Bonasio, Juergen Liebig, Shelley L. Berger, Danny Reinberg

Research output: Contribution to journalReview article

85 Scopus citations

Abstract

Understanding the molecular basis of how behavioural states are established, maintained and altered by environmental cues is an area of considerable and growing interest. Epigenetic processes, including methylation of DNA and post-translational modification of histones, dynamically modulate activity-dependent gene expression in neurons and can therefore have important regulatory roles in shaping behavioural responses to environmental cues. Several eusocial insect species-with their unique displays of behavioural plasticity due to age, morphology and social context-have emerged as models to investigate the genetic and epigenetic underpinnings of animal social behaviour. This Review summarizes recent studies in the epigenetics of social behaviour and offers perspectives on emerging trends and prospects for establishing genetic tools in eusocial insects.

Original languageEnglish (US)
Pages (from-to)677-688
Number of pages12
JournalNature Reviews Genetics
Volume15
Issue number10
DOIs
StatePublished - Oct 11 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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    Yan, H., Simola, D. F., Bonasio, R., Liebig, J., Berger, S. L., & Reinberg, D. (2014). Eusocial insects as emerging models for behavioural epigenetics. Nature Reviews Genetics, 15(10), 677-688. https://doi.org/10.1038/nrg3787