Eusocial insects as emerging models for behavioural epigenetics

Hua Yan, Daniel F. Simola, Roberto Bonasio, Juergen Liebig, Shelley L. Berger, Danny Reinberg

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Understanding the molecular basis of how behavioural states are established, maintained and altered by environmental cues is an area of considerable and growing interest. Epigenetic processes, including methylation of DNA and post-translational modification of histones, dynamically modulate activity-dependent gene expression in neurons and can therefore have important regulatory roles in shaping behavioural responses to environmental cues. Several eusocial insect species-with their unique displays of behavioural plasticity due to age, morphology and social context-have emerged as models to investigate the genetic and epigenetic underpinnings of animal social behaviour. This Review summarizes recent studies in the epigenetics of social behaviour and offers perspectives on emerging trends and prospects for establishing genetic tools in eusocial insects.

Original languageEnglish (US)
Pages (from-to)677-688
Number of pages12
JournalNature Reviews Genetics
Volume15
Issue number10
DOIs
StatePublished - Oct 11 2014

Fingerprint

Social Behavior
Epigenomics
Cues
Insects
Genetic Epigenesis
Animal Behavior
DNA Methylation
Post Translational Protein Processing
Histones
Gene Expression
Neurons

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)
  • Molecular Biology
  • Medicine(all)

Cite this

Yan, H., Simola, D. F., Bonasio, R., Liebig, J., Berger, S. L., & Reinberg, D. (2014). Eusocial insects as emerging models for behavioural epigenetics. Nature Reviews Genetics, 15(10), 677-688. https://doi.org/10.1038/nrg3787

Eusocial insects as emerging models for behavioural epigenetics. / Yan, Hua; Simola, Daniel F.; Bonasio, Roberto; Liebig, Juergen; Berger, Shelley L.; Reinberg, Danny.

In: Nature Reviews Genetics, Vol. 15, No. 10, 11.10.2014, p. 677-688.

Research output: Contribution to journalArticle

Yan, H, Simola, DF, Bonasio, R, Liebig, J, Berger, SL & Reinberg, D 2014, 'Eusocial insects as emerging models for behavioural epigenetics', Nature Reviews Genetics, vol. 15, no. 10, pp. 677-688. https://doi.org/10.1038/nrg3787
Yan, Hua ; Simola, Daniel F. ; Bonasio, Roberto ; Liebig, Juergen ; Berger, Shelley L. ; Reinberg, Danny. / Eusocial insects as emerging models for behavioural epigenetics. In: Nature Reviews Genetics. 2014 ; Vol. 15, No. 10. pp. 677-688.
@article{05eb68ed78e244a29e79caea746cf511,
title = "Eusocial insects as emerging models for behavioural epigenetics",
abstract = "Understanding the molecular basis of how behavioural states are established, maintained and altered by environmental cues is an area of considerable and growing interest. Epigenetic processes, including methylation of DNA and post-translational modification of histones, dynamically modulate activity-dependent gene expression in neurons and can therefore have important regulatory roles in shaping behavioural responses to environmental cues. Several eusocial insect species-with their unique displays of behavioural plasticity due to age, morphology and social context-have emerged as models to investigate the genetic and epigenetic underpinnings of animal social behaviour. This Review summarizes recent studies in the epigenetics of social behaviour and offers perspectives on emerging trends and prospects for establishing genetic tools in eusocial insects.",
author = "Hua Yan and Simola, {Daniel F.} and Roberto Bonasio and Juergen Liebig and Berger, {Shelley L.} and Danny Reinberg",
year = "2014",
month = "10",
day = "11",
doi = "10.1038/nrg3787",
language = "English (US)",
volume = "15",
pages = "677--688",
journal = "Nature Reviews Genetics",
issn = "1471-0056",
publisher = "Nature Publishing Group",
number = "10",

}

TY - JOUR

T1 - Eusocial insects as emerging models for behavioural epigenetics

AU - Yan, Hua

AU - Simola, Daniel F.

AU - Bonasio, Roberto

AU - Liebig, Juergen

AU - Berger, Shelley L.

AU - Reinberg, Danny

PY - 2014/10/11

Y1 - 2014/10/11

N2 - Understanding the molecular basis of how behavioural states are established, maintained and altered by environmental cues is an area of considerable and growing interest. Epigenetic processes, including methylation of DNA and post-translational modification of histones, dynamically modulate activity-dependent gene expression in neurons and can therefore have important regulatory roles in shaping behavioural responses to environmental cues. Several eusocial insect species-with their unique displays of behavioural plasticity due to age, morphology and social context-have emerged as models to investigate the genetic and epigenetic underpinnings of animal social behaviour. This Review summarizes recent studies in the epigenetics of social behaviour and offers perspectives on emerging trends and prospects for establishing genetic tools in eusocial insects.

AB - Understanding the molecular basis of how behavioural states are established, maintained and altered by environmental cues is an area of considerable and growing interest. Epigenetic processes, including methylation of DNA and post-translational modification of histones, dynamically modulate activity-dependent gene expression in neurons and can therefore have important regulatory roles in shaping behavioural responses to environmental cues. Several eusocial insect species-with their unique displays of behavioural plasticity due to age, morphology and social context-have emerged as models to investigate the genetic and epigenetic underpinnings of animal social behaviour. This Review summarizes recent studies in the epigenetics of social behaviour and offers perspectives on emerging trends and prospects for establishing genetic tools in eusocial insects.

UR - http://www.scopus.com/inward/record.url?scp=84922248875&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922248875&partnerID=8YFLogxK

U2 - 10.1038/nrg3787

DO - 10.1038/nrg3787

M3 - Article

VL - 15

SP - 677

EP - 688

JO - Nature Reviews Genetics

JF - Nature Reviews Genetics

SN - 1471-0056

IS - 10

ER -