Ethanol, Glutamate, and the Ventral Tegmental Area-A Commentary on

Ding, Engleman, Rodd, and McBride, "Ethanol Increases Glutamate Neurotransmission in the Posterior Ventral Tegmental Area of Female Wistar Rats"

Research output: Contribution to journalArticle

Abstract

The recent study by Ding and colleagues (2012) utilized in vivo microdialysis to demonstrate that acute and repeated alcohol administration produces dose-dependent effects on extracellular levels of the glutamate in the posterior ventral tegmental area. These findings have important implications for interactions between glutamatergic and dopaminergic mediation of alcohol reinforcement in the ventral midbrain.

Original languageEnglish (US)
Pages (from-to)453-454
Number of pages2
JournalAlcoholism: Clinical and Experimental Research
Volume36
Issue number6
DOIs
StatePublished - Jun 2012

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Ventral Tegmental Area
Synaptic Transmission
Wistar Rats
Rats
Glutamic Acid
Ethanol
Alcohols
Microdialysis
Mesencephalon
Reinforcement

Keywords

  • Glutamate
  • Microdialysis
  • Reinforcement
  • Ventral Tegmental Area

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health
  • Toxicology

Cite this

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abstract = "The recent study by Ding and colleagues (2012) utilized in vivo microdialysis to demonstrate that acute and repeated alcohol administration produces dose-dependent effects on extracellular levels of the glutamate in the posterior ventral tegmental area. These findings have important implications for interactions between glutamatergic and dopaminergic mediation of alcohol reinforcement in the ventral midbrain.",
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