Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome

Medicine & Life Sciences

• Down Syndrome 85%
• Cholinergic Agents 77%
• Estrogens 67%
• Cognition 65%
• Animal Models 59%
• Basal Forebrain 59%
• Phenotype 49%
• Estrogen Replacement Therapy 43%
• Cholinergic Neurons 28%
• Alzheimer Disease 27%
• Trisomy Chromosome 16 19%
• Reversal Learning 16%
• Choline O-Acetyltransferase 14%
• Nerve Growth Factor 12%
• Menopause 12%
• Cell Size 12%
• Dementia 9%
• Cognitive Dysfunction 9%
• Intercellular Signaling Peptides and Proteins 9%
• Young Adult 9%
• Learning 8%
• Neurons 7%
• Therapeutics 5%
• Proteins 4%

Social Sciences

• Down Syndrome 100%
• dementia 82%
• cognition 67%
• animal 66%
• menopause 26%
• young adult 17%
• flexibility 16%
• learning 13%
• evaluation 9%
• evidence 8%