Estimation of parameters governing the transmission dynamics of schistosomes

Z. Feng, A. Eppert, Fabio Milner, D. J. Minchella

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The clumping parameter related to the distribution of schistosome parasites is obtained by fitting a negative binomial distribution to data collected from patients in a village in Brazil; the natural uninfected and parasite-induced snail host mortality rates are obtained from laboratory data. These values are used in a schistosomiasis model proposed earlier by the authors, and a disease transmission parameter from snails to humans is estimated. Finally, the effect of chemotherapy of humans is assessed using prevalence of morbidity as a measure of the level of schistosome infection in a human population.

Original languageEnglish (US)
Pages (from-to)1105-1112
Number of pages8
JournalApplied Mathematics Letters
Volume17
Issue number10
DOIs
StatePublished - 2004
Externally publishedYes

Fingerprint

Chemotherapy
Negative binomial distribution
Morbidity
Mortality Rate
Infection
Human
Parasites
Model

Keywords

  • Control strategy
  • Mathematical model
  • Parameter estimation
  • Schistosomiasis

ASJC Scopus subject areas

  • Computational Mechanics
  • Control and Systems Engineering
  • Applied Mathematics
  • Numerical Analysis

Cite this

Estimation of parameters governing the transmission dynamics of schistosomes. / Feng, Z.; Eppert, A.; Milner, Fabio; Minchella, D. J.

In: Applied Mathematics Letters, Vol. 17, No. 10, 2004, p. 1105-1112.

Research output: Contribution to journalArticle

Feng, Z. ; Eppert, A. ; Milner, Fabio ; Minchella, D. J. / Estimation of parameters governing the transmission dynamics of schistosomes. In: Applied Mathematics Letters. 2004 ; Vol. 17, No. 10. pp. 1105-1112.
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