Estimation of parameters governing the transmission dynamics of schistosomes

Z. Feng, A. Eppert, F. A. Milner, D. J. Minchella

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

The clumping parameter related to the distribution of schistosome parasites is obtained by fitting a negative binomial distribution to data collected from patients in a village in Brazil; the natural uninfected and parasite-induced snail host mortality rates are obtained from laboratory data. These values are used in a schistosomiasis model proposed earlier by the authors, and a disease transmission parameter from snails to humans is estimated. Finally, the effect of chemotherapy of humans is assessed using prevalence of morbidity as a measure of the level of schistosome infection in a human population.

Original languageEnglish (US)
Pages (from-to)1105-1112
Number of pages8
JournalApplied Mathematics Letters
Volume17
Issue number10
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

    Fingerprint

Keywords

  • Control strategy
  • Mathematical model
  • Parameter estimation
  • Schistosomiasis

ASJC Scopus subject areas

  • Applied Mathematics

Cite this