Abstract
Biomarkers promise biomolecular explanations as well as reliable diagnostics, stratification, and treatment strategies that have the potential to help mitigate the effects of disorders. While no reliable biomarker has yet been found for autism spectrum disorder (ASD), fatty acids have been investigated as potential biomarkers because of their association with brain development and neural functions. However, the ability of fatty acids to classify individuals with ASD from age/gender-matched neurotypical (NEU) peers has largely been ignored in favor of investigating population-level differences. Contrary to existing work, this classification task between ASD and NEU cohorts is the main focus of this work. The data presented herein suggest that fatty acids do not allow for classification at the individual level.
Original language | English (US) |
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Article number | 12 |
Journal | Biomarker Research |
Volume | 6 |
Issue number | 1 |
DOIs | |
State | Published - Mar 14 2018 |
Keywords
- Autism spectrum disorder
- Diagnostic biomarkers
- Fatty acids
- Multivariate statistical analysis
ASJC Scopus subject areas
- Molecular Medicine
- Clinical Biochemistry
- Biochemistry, medical
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Dive into the research topics of 'Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: A case control study'. Together they form a unique fingerprint.Datasets
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Additional file 1 of Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: a case control study
Howsmon, D. P. (Creator), Adams, J. (Creator), Kruger, U. (Creator), Geis, E. (Creator), Gehn, E. (Creator), Hahn, J. (Contributor) & Juergen, H. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.5985733, https://springernature.figshare.com/articles/Additional_file_1_of_Erythrocyte_fatty_acid_profiles_in_children_are_not_predictive_of_autism_spectrum_disorder_status_a_case_control_study/5985733
Dataset
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Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: a case control study
Howsmon, D. P. (Creator), Adams, J. (Creator), Kruger, U. (Creator), Geis, E. (Creator), Gehn, E. (Creator), Hahn, J. (Contributor) & Juergen, H. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4032256, https://figshare.com/collections/Erythrocyte_fatty_acid_profiles_in_children_are_not_predictive_of_autism_spectrum_disorder_status_a_case_control_study/4032256
Dataset
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Additional file 1 of Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: a case control study
Howsmon, D. P. (Creator), Adams, J. (Creator), Kruger, U. (Creator), Geis, E. (Creator), Gehn, E. (Creator), Hahn, J. (Contributor) & Juergen, H. (Contributor), figshare Academic Research System, 2018
DOI: 10.6084/m9.figshare.5985733.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Erythrocyte_fatty_acid_profiles_in_children_are_not_predictive_of_autism_spectrum_disorder_status_a_case_control_study/5985733/1
Dataset