Enzymatic cleavage of RNA by RNA

Sidney Altman, Madeline Baer, Cecilia Guerrier-Takada, Agustin Vioque

Research output: Contribution to journalReview article

47 Citations (Scopus)

Abstract

The catalytic activity of E. coli RNase P, an enzyme essential for tRNA biosynthesis in vivo, resides in the RNA subunit of the enzyme. This RNA, which has all the properties of a classical enzyme, can cleave precursor tRNAs in vitro in the total absence of proteins.

Original languageEnglish (US)
Pages (from-to)515-518
Number of pages4
JournalTrends in Biochemical Sciences
Volume11
Issue number12
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

RNA Cleavage
RNA
Enzymes
Ribonuclease P
Biosynthesis
RNA Precursors
Transfer RNA
Escherichia coli
Catalyst activity
Proteins

ASJC Scopus subject areas

  • Biochemistry

Cite this

Enzymatic cleavage of RNA by RNA. / Altman, Sidney; Baer, Madeline; Guerrier-Takada, Cecilia; Vioque, Agustin.

In: Trends in Biochemical Sciences, Vol. 11, No. 12, 1986, p. 515-518.

Research output: Contribution to journalReview article

Altman, S, Baer, M, Guerrier-Takada, C & Vioque, A 1986, 'Enzymatic cleavage of RNA by RNA' Trends in Biochemical Sciences, vol. 11, no. 12, pp. 515-518. https://doi.org/10.1016/0968-0004(86)90086-1
Altman, Sidney ; Baer, Madeline ; Guerrier-Takada, Cecilia ; Vioque, Agustin. / Enzymatic cleavage of RNA by RNA. In: Trends in Biochemical Sciences. 1986 ; Vol. 11, No. 12. pp. 515-518.
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