Environmentally responsive injectable materials

H. H. Bearat, Brent Vernon

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Abstract

This chapter highlights the various environmental stimuli which can be utilized as a trigger for in situ formation of injectable hydrogel systems, specifically to provide a more efficient and localized method for controlled delivery of drugs and molecules. These components include temperature, electric field, pH, light, magnetic field, pressure and ionic strength, as well as biomolecular stimuli such as antigens, enzymes, thrombin, and glucose. The properties of each stimulus are described as well as their particular uses in biomedical applications.

Original languageEnglish (US)
Title of host publicationInjectable Biomaterials
Subtitle of host publicationScience and Applications
PublisherElsevier Inc.
Pages263-297
Number of pages35
ISBN (Print)9781845695880
DOIs
StatePublished - Jan 2011

Keywords

  • Antigen
  • Electric field
  • Enzyme
  • Glucose
  • Hydrogel
  • Ionic strength
  • Light
  • Magnetic field
  • PH
  • Poly(N-isopropyl acrylamide)
  • Pressure
  • Temperature
  • Thrombin

ASJC Scopus subject areas

  • General Materials Science

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