Endoscopic system for simultaneous visual examination and electronic detection of fluorescence

J. H. Kinsey, D. A. Cortese

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

A sensitive parallel system for visual examination of a target area with simultaneous detection and measurement of fluorescent emission from the same region is described. This device, originally designed and constructed for bronchial cancer detection, alternates visual illumination and narrow band excitation radiation in conjunction with a synchronously shuttered PMT at frequencies above the visual flicker fusion threshold to provide parallel operation. The signal from the PMT is synchronously amplified using a lock-in amplifier, the dc output of which is voltage-to-frequency converted and amplified to provide an audible tone whose frequency is proportional to the fluorescence sensed.

Original languageEnglish (US)
Pages (from-to)1403-1406
Number of pages4
JournalReview of Scientific Instruments
Volume51
Issue number10
DOIs
StatePublished - Dec 1 1980
Externally publishedYes

ASJC Scopus subject areas

  • Instrumentation

Fingerprint Dive into the research topics of 'Endoscopic system for simultaneous visual examination and electronic detection of fluorescence'. Together they form a unique fingerprint.

  • Cite this