Endocrine and cardiovascular responses during phobic anxiety

Randolph Nesse, G. C. Curtis, B. A. Thyer, D. S. McCann, M. J. Huber-Smith, R. F. Knopf

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

In vivo exposure therapy for phobias is uniquely suited for controlled studies of endocrine and physiologic responses during psychologic stress. In this study, exposure therapy induced significant increases in subjective anxiety, pulse, blood pressure, plasma norepinephrine, epinephrine, insulin, cortisol, and growth hormone, but did not change plasma glucagon or pancreatic polypeptide. Although the subjective and behavioral manifestations of anxiety were consistent and intense, the magnitude, consistency, timing, and concordance of endocrine and cardiovascular responses showed considerable variation.

Original languageEnglish (US)
Pages (from-to)320-332
Number of pages13
JournalPsychosomatic Medicine
Volume47
Issue number4
StatePublished - 1985
Externally publishedYes

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Implosive Therapy
Anxiety
Blood Pressure
Pancreatic Polypeptide
Phobic Disorders
Glucagon
Psychological Stress
Epinephrine
Growth Hormone
Hydrocortisone
Norepinephrine
Insulin

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Nesse, R., Curtis, G. C., Thyer, B. A., McCann, D. S., Huber-Smith, M. J., & Knopf, R. F. (1985). Endocrine and cardiovascular responses during phobic anxiety. Psychosomatic Medicine, 47(4), 320-332.

Endocrine and cardiovascular responses during phobic anxiety. / Nesse, Randolph; Curtis, G. C.; Thyer, B. A.; McCann, D. S.; Huber-Smith, M. J.; Knopf, R. F.

In: Psychosomatic Medicine, Vol. 47, No. 4, 1985, p. 320-332.

Research output: Contribution to journalArticle

Nesse, R, Curtis, GC, Thyer, BA, McCann, DS, Huber-Smith, MJ & Knopf, RF 1985, 'Endocrine and cardiovascular responses during phobic anxiety', Psychosomatic Medicine, vol. 47, no. 4, pp. 320-332.
Nesse R, Curtis GC, Thyer BA, McCann DS, Huber-Smith MJ, Knopf RF. Endocrine and cardiovascular responses during phobic anxiety. Psychosomatic Medicine. 1985;47(4):320-332.
Nesse, Randolph ; Curtis, G. C. ; Thyer, B. A. ; McCann, D. S. ; Huber-Smith, M. J. ; Knopf, R. F. / Endocrine and cardiovascular responses during phobic anxiety. In: Psychosomatic Medicine. 1985 ; Vol. 47, No. 4. pp. 320-332.
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