Emerging roles of β-arrestins

F. Gregory Buchanan, Raymond N. DuBois

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

Original languageEnglish (US)
Pages (from-to)2060-2063
Number of pages4
JournalCell Cycle
Volume5
Issue number18
DOIs
StatePublished - Sep 15 2006

    Fingerprint

Keywords

  • Arrestin
  • B-Arrestin
  • Development
  • EGFR
  • Metastasis
  • Migration
  • Nuclear
  • Review
  • Src
  • Wnt

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

Cite this

Buchanan, F. G., & DuBois, R. N. (2006). Emerging roles of β-arrestins. Cell Cycle, 5(18), 2060-2063. https://doi.org/10.4161/cc.5.18.3212