Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Sep 15 2006|
ASJC Scopus subject areas
- Molecular Biology
- Developmental Biology
- Cell Biology