Emerging roles of β-arrestins

F. Gregory Buchanan, Raymond N. DuBois

    Research output: Contribution to journalReview articlepeer-review

    31 Scopus citations

    Abstract

    Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

    Original languageEnglish (US)
    Pages (from-to)2060-2063
    Number of pages4
    JournalCell Cycle
    Volume5
    Issue number18
    DOIs
    StatePublished - Sep 15 2006

    Keywords

    • Arrestin
    • B-Arrestin
    • Development
    • EGFR
    • Metastasis
    • Migration
    • Nuclear
    • Review
    • Src
    • Wnt

    ASJC Scopus subject areas

    • Molecular Biology
    • Developmental Biology
    • Cell Biology

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