Abstract
Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.
Original language | English (US) |
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Pages (from-to) | 2060-2063 |
Number of pages | 4 |
Journal | Cell Cycle |
Volume | 5 |
Issue number | 18 |
DOIs | |
State | Published - Sep 15 2006 |
Externally published | Yes |
Keywords
- Arrestin
- B-Arrestin
- Development
- EGFR
- Metastasis
- Migration
- Nuclear
- Review
- Src
- Wnt
ASJC Scopus subject areas
- Molecular Biology
- Developmental Biology
- Cell Biology