Emerging roles of β-arrestins

F. Gregory Buchanan; Raymond N. DuBois

doi:10.4161/cc.5.18.3212

Emerging roles of β-arrestins

F. Gregory Buchanan, Raymond N. DuBois

Research output: Contribution to journal › Review article › peer-review

34 Scopus citations

Abstract

Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

Original language	English (US)
Pages (from-to)	2060-2063
Number of pages	4
Journal	Cell Cycle
Volume	5
Issue number	18
DOIs	https://doi.org/10.4161/cc.5.18.3212
State	Published - Sep 15 2006
Externally published	Yes

Keywords

Arrestin
B-Arrestin
Development
EGFR
Metastasis
Migration
Nuclear
Review
Src
Wnt

ASJC Scopus subject areas

Molecular Biology
Developmental Biology
Cell Biology

Access to Document

10.4161/cc.5.18.3212

Cite this

@article{e93cb5480d2245bf8dc35271855d25e4,

title = "Emerging roles of β-arrestins",

abstract = "Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.",

keywords = "Arrestin, B-Arrestin, Development, EGFR, Metastasis, Migration, Nuclear, Review, Src, Wnt",

author = "Buchanan, {F. Gregory} and DuBois, {Raymond N.}",

year = "2006",

month = sep,

day = "15",

doi = "10.4161/cc.5.18.3212",

language = "English (US)",

volume = "5",

pages = "2060--2063",

journal = "Cell Cycle",

issn = "1538-4101",

publisher = "Landes Bioscience",

number = "18",

}

TY - JOUR

T1 - Emerging roles of β-arrestins

AU - Buchanan, F. Gregory

AU - DuBois, Raymond N.

PY - 2006/9/15

Y1 - 2006/9/15

N2 - Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

AB - Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

KW - Arrestin

KW - B-Arrestin

KW - Development

KW - EGFR

KW - Metastasis

KW - Migration

KW - Nuclear

KW - Review

KW - Src

KW - Wnt

UR - http://www.scopus.com/inward/record.url?scp=33749652386&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749652386&partnerID=8YFLogxK

U2 - 10.4161/cc.5.18.3212

DO - 10.4161/cc.5.18.3212

M3 - Review article

C2 - 16969081

AN - SCOPUS:33749652386

SN - 1538-4101

VL - 5

SP - 2060

EP - 2063

JO - Cell Cycle

JF - Cell Cycle

IS - 18

ER -

Emerging roles of β-arrestins

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this