Electronic Decay Length in a Protein Molecule

Bintian Zhang, Stuart Lindsay

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Antibodies have two identical binding domains and can therefore form a well-defined conducting bridge by binding a pair of electrodes functionalized with an epitope. The conductance measured between these two fixed points on the antibody does not change with the size of the electrode gap. A second conduction path is via one specific attachment to an epitope and a second nonspecific attachment to the surface of the antibody. In this case, the conductance does change with gap size, yielding an estimated electronic decay length >6 nm, long enough that it is not possible to distinguish between an exponential or a hyperbolic distance dependence. This decay length is substantially greater than that measured for hopping transport in an organic molecular wire.

Original languageEnglish (US)
Pages (from-to)4017-4022
Number of pages6
JournalNano Letters
Volume19
Issue number6
DOIs
StatePublished - Jun 12 2019
Externally publishedYes

Fingerprint

antibodies
Antibodies
Epitopes
proteins
Proteins
Molecules
attachment
decay
electronics
conduction
molecules
Electrodes
electrodes
wire
Wire

Keywords

  • bioelectronics
  • electronic decay length
  • Molecular electronics
  • protein conductance

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

Cite this

Electronic Decay Length in a Protein Molecule. / Zhang, Bintian; Lindsay, Stuart.

In: Nano Letters, Vol. 19, No. 6, 12.06.2019, p. 4017-4022.

Research output: Contribution to journalArticle

Zhang, Bintian ; Lindsay, Stuart. / Electronic Decay Length in a Protein Molecule. In: Nano Letters. 2019 ; Vol. 19, No. 6. pp. 4017-4022.
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