Electron microscopy at 1-Å resolution by entropy maximization and likelihood ranking

W. Dong, T. Baird, J. R. Fryer, C. J. Gilmore, D. D. MacNicol, G. Bricogne, David Smith, M. A. O'Keefe, S. Hövmoller

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations

    Abstract

    The resolution of electron microscopy may be extended by combining the phase information in microscope images with electron diffraction intensities. A general method for obtaining structural reconstructions at a resolution greater than that of the phase information is demonstrated for crystals of perchlorocoronene. By using entropy maximization methods combined with likelihood ranking, the resolution is extended from 0.32 nm in the microscope images to 0.1 nm in the reconstruction from phase and intensity data.

    Original languageEnglish (US)
    Pages (from-to)605-609
    Number of pages5
    JournalNature
    Volume355
    Issue number6361
    DOIs
    StatePublished - 1992

    ASJC Scopus subject areas

    • General

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