EIR1, a root-specific protein involved in auxin transport, is required for gravitropism in Arabidopsis thaliana

Christian Luschnig, Roberto Gaxiola, Paula Grisafi, Gerald R. Fink

Research output: Contribution to journalArticle

575 Citations (Scopus)

Abstract

The EIR1 gene of Arabidopsis is a member of a family of plant genes with similarities to bacterial membrane transporters. This gene is expressed only in the root, which is consistent with the phenotypes of the eir1 mutants-the roots are agravitropic and have a reduced sensitivity to ethylene. The roots of eir1 mutants are also insensitive to the excess auxin produced by alf1-1 and fail to induce an auxin-inducible gene in the expansion zone. Although they fail to respond to internally generated auxin, they respond normally to externally applied auxin. Expression of the EIR1 gene in Saccharomyces cerevisiae confers resistance to fluorinated indolic compounds. Taken together, these data suggest that the EIR1 protein has a root-specific role in the transport of auxin.

Original languageEnglish (US)
Pages (from-to)2175-2187
Number of pages13
JournalGenes and Development
Volume12
Issue number14
StatePublished - Jul 15 1998
Externally publishedYes

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Gravitropism
Indoleacetic Acids
Arabidopsis
Proteins
Genes
Plant Genes
Membrane Transport Proteins
Saccharomyces cerevisiae
Phenotype
Gene Expression

Keywords

  • Auxin
  • Auxin transport inhibitors
  • Ethylene
  • Membrane protein
  • Root gravitropism

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

Cite this

EIR1, a root-specific protein involved in auxin transport, is required for gravitropism in Arabidopsis thaliana. / Luschnig, Christian; Gaxiola, Roberto; Grisafi, Paula; Fink, Gerald R.

In: Genes and Development, Vol. 12, No. 14, 15.07.1998, p. 2175-2187.

Research output: Contribution to journalArticle

Luschnig, Christian ; Gaxiola, Roberto ; Grisafi, Paula ; Fink, Gerald R. / EIR1, a root-specific protein involved in auxin transport, is required for gravitropism in Arabidopsis thaliana. In: Genes and Development. 1998 ; Vol. 12, No. 14. pp. 2175-2187.
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