Egg desiccation leads to dehydration and enhanced innate immunity in python embryos

George A. Brusch, Dale Denardo

Research output: Contribution to journalArticle

Abstract

The immune system is essential for survival and its performance can vary depending on the physiological state of the organism. Much of the current research into immune function dynamics has examined newborn to adult life stages, despite previous studies documenting physiological responses in embryos to environmental stimuli. While energy balance has been the predominant focus as the driver of changes in immune function, recent research has found a positive relationship between dehydration and innate immune performance in adult reptiles. We expanded the understanding of this relationship by examining trans-generational immune effects of female dehydration as well as the effects of egg desiccation on embryonic hydration state and innate immunity using Children's pythons, Antaresia childreni. We used a 2 × 2 experiment with hydrated or dehydrated mothers and eggs either incubated under continuous optimal conditions or experiencing desiccating conditions for 24 h. Our results demonstrate that, similar to adults, embryos enhance some metrics of innate immunity when they are dehydrated.

LanguageEnglish (US)
Pages147-151
Number of pages5
JournalDevelopmental and Comparative Immunology
Volume90
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Boidae
Desiccation
Dehydration
Innate Immunity
Ovum
Embryonic Structures
Reptiles
Research
Eggs
Immune System
Mothers
Newborn Infant

Keywords

  • Dehydration
  • Embryonic immunity
  • Immunocompetence
  • Innate immunity

ASJC Scopus subject areas

  • Immunology
  • Developmental Biology

Cite this

Egg desiccation leads to dehydration and enhanced innate immunity in python embryos. / Brusch, George A.; Denardo, Dale.

In: Developmental and Comparative Immunology, Vol. 90, 01.01.2019, p. 147-151.

Research output: Contribution to journalArticle

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