Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays

Nipun Thamatam; Jennifer Blain Christen

doi:10.1109/HI-POCT45284.2019.8962702

Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Lateral Flow Immunoassays (LFIAs) are among the most successful Point of Care (POC) tests. However, factors like reagent stability, reaction rates, and binding kinetics limit the performance and robustness of LFIAs. One of the factors that affects the overall performance of LFIA is the fluid flow rate, and hence, it is desirable to maintain a predictable fluid velocity in porous media. The main objective of this study is to build a statistical model that estimates the fluid velocity in porous media for any given ambient condition to enable us to determine the optimal design parameters for achieving a desired fluid velocity in porous media.

Original language	English (US)
Title of host publication	2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	75-79
Number of pages	5
ISBN (Electronic)	9781728138121
DOIs	https://doi.org/10.1109/HI-POCT45284.2019.8962702
State	Published - Nov 2019
Externally published	Yes
Event	2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019 - Bethesda, United States Duration: Nov 20 2019 → Nov 22 2019

Publication series

Name	2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019

Conference

Conference	2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019
Country/Territory	United States
City	Bethesda
Period	11/20/19 → 11/22/19

Keywords

design of experiments
evaporation
fluid flow rate
geometry
porous media

ASJC Scopus subject areas

Artificial Intelligence
Computer Science Applications
Biomedical Engineering
Health Informatics
Instrumentation
Health(social science)

Access to Document

10.1109/HI-POCT45284.2019.8962702

Cite this

Thamatam, N., & Christen, J. B. (2019). Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays. In 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019 (pp. 75-79). Article 8962702 (2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/HI-POCT45284.2019.8962702

Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays. / Thamatam, Nipun; Christen, Jennifer Blain.
2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 75-79 8962702 (2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Thamatam, N & Christen, JB 2019, Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays. in 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019., 8962702, 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019, Institute of Electrical and Electronics Engineers Inc., pp. 75-79, 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019, Bethesda, United States, 11/20/19. https://doi.org/10.1109/HI-POCT45284.2019.8962702

Thamatam N, Christen JB. Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays. In 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 75-79. 8962702. (2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019). doi: 10.1109/HI-POCT45284.2019.8962702

Thamatam, Nipun ; Christen, Jennifer Blain. / Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays. 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 75-79 (2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019).

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title = "Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays",

abstract = "Lateral Flow Immunoassays (LFIAs) are among the most successful Point of Care (POC) tests. However, factors like reagent stability, reaction rates, and binding kinetics limit the performance and robustness of LFIAs. One of the factors that affects the overall performance of LFIA is the fluid flow rate, and hence, it is desirable to maintain a predictable fluid velocity in porous media. The main objective of this study is to build a statistical model that estimates the fluid velocity in porous media for any given ambient condition to enable us to determine the optimal design parameters for achieving a desired fluid velocity in porous media.",

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AB - Lateral Flow Immunoassays (LFIAs) are among the most successful Point of Care (POC) tests. However, factors like reagent stability, reaction rates, and binding kinetics limit the performance and robustness of LFIAs. One of the factors that affects the overall performance of LFIA is the fluid flow rate, and hence, it is desirable to maintain a predictable fluid velocity in porous media. The main objective of this study is to build a statistical model that estimates the fluid velocity in porous media for any given ambient condition to enable us to determine the optimal design parameters for achieving a desired fluid velocity in porous media.

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KW - geometry

KW - porous media

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Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this