Effects of in vivo corticosterone treatment on the in vitro metabolism of testosterone in the comb and brain of the young male chicken

Pierre Deviche, J. Balthazart, G. Malacarne, J. C. Hendrick

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Male chickens kept in constant light were injected from their second to their 12th day of life daily either with 2.5 mg of corticosterone or with a control solution. In both groups of birds, the in vivo metabolism of labeled testosterone by the comb and by brain tissues (hyperstriatum, hypothalamus, pituitary gland) was then studied. The experimental treatment blocked the growth of the comb observed in control birds. In this tissue, it also reduced the production from testosterone of 5α-dihydrotestosterone and of 5α-androstane-3α,17β-diol, but it increased the production of 5β-androstane-3α,17β-diol. These modifications did not appear in any brain tissue; they were not accompanied by changes either of LH or of testosterone circulating levels or of the testes' weights.

Original languageEnglish (US)
Pages (from-to)398-402
Number of pages5
JournalGeneral and Comparative Endocrinology
Volume48
Issue number3
DOIs
StatePublished - 1982
Externally publishedYes

Fingerprint

Comb and Wattles
Androstane-3,17-diol
corticosterone
Corticosterone
testosterone
Testosterone
Chickens
glycols
chickens
brain
metabolism
Birds
Brain
Dihydrotestosterone
bird control
pituitary gland
Pituitary Gland
hypothalamus
Hypothalamus
Testis

ASJC Scopus subject areas

  • Endocrinology

Cite this

Effects of in vivo corticosterone treatment on the in vitro metabolism of testosterone in the comb and brain of the young male chicken. / Deviche, Pierre; Balthazart, J.; Malacarne, G.; Hendrick, J. C.

In: General and Comparative Endocrinology, Vol. 48, No. 3, 1982, p. 398-402.

Research output: Contribution to journalArticle

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