Effects of deformability, uneven surface charge distributions, and multipole moments on biocolloid electrophoretic migration

Michele D. Pysher, Mark Hayes

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Liposomes have been widely used as cellular and bioparticle mimics due to their lipid bilayer structure and relative ease of production and manipulation. Such biocolloids are frequently characterized by capillary electrophoresis (CE), which promises a wealth of information about such properties as surface charge, composition, and rigidity. The applicability of this information is somewhat limited, however, since it is interpreted with colloidal theories that do not account for the unique properties of biocolloids. In this work, the effects of deformability, mobile surface charges, intrinsic polarizability, and uneven surface charge distributions are incorporated into colloidal theories in order to better model the electrophoretic behaviors of liposomes.

Original languageEnglish (US)
Pages (from-to)3572-3577
Number of pages6
JournalLangmuir
Volume21
Issue number8
DOIs
StatePublished - Apr 12 2005

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Charge distribution
Surface charge
Formability
charge distribution
multipoles
Liposomes
moments
Capillary electrophoresis
Lipid bilayers
electrophoresis
rigidity
Rigidity
lipids
manipulators
Chemical analysis

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

Cite this

Effects of deformability, uneven surface charge distributions, and multipole moments on biocolloid electrophoretic migration. / Pysher, Michele D.; Hayes, Mark.

In: Langmuir, Vol. 21, No. 8, 12.04.2005, p. 3572-3577.

Research output: Contribution to journalArticle

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