Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent

Wei Zhang, Jamie A. Johnston, Mark A. Ross, Kyle Sanniec, Elizabeth A. Gleason, Amylou C. Dueck, Marco Santello

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Carpal tunnel syndrome (CTS) impairs sensation of a subset of digits. Although the effects of CTS on manipulation performed with CTS-affected digits have been studied using precision grip tasks, the extent to which CTS affects multi-digit force coordination has only recently been studied. Whole-hand manipulation studies have shown that CTS patients retain the ability to modulate multi-digit forces to object mass, mass distribution, and texture. However, CTS results in sensorimotor deficits relative to healthy controls, including significantly larger grip force and lower ability to balance the torques generated by the digits. Here we investigated the effects of CTS on multi-digit force modulation to object weight when manipulating an object with a variable number of fingers. We hypothesized that CTS patients would be able to modulate digit forces to object weight. However, as different grip types involve the exclusive use of CTS-affected digits ('uniform' grips) or a combination of CTS-affected and non-affected digits ('mixed' grips), we addressed the question of whether 'mixed' grips would reduce or worsen CTS-induced force coordination deficits. The former scenario would be due to adding digits with intact tactile feedback, whereas the latter scenario might occur due to a potentially greater challenge for the central nervous system of integrating 'noisy' and intact tactile feedback. CTS patients learned multi-digit force modulation to object weight regardless of grip type. Although controls exerted the same total grip force across all grip types, patients exerted significantly larger grip force than controls but only for manipulations with four and five digits. Importantly, this effect was due to CTS patients' inability to change the finger force distribution when adding the ring and little fingers. These findings suggest that CTS primarily challenges sensorimotor integration processes for dexterous manipulation underlying the coordination of CTS-affected and non-affected digits.

Original languageEnglish (US)
Article numbere53751
JournalPLoS One
Volume8
Issue number1
DOIs
StatePublished - Jan 17 2013

Fingerprint

Carpal Tunnel Syndrome
Hand Strength
Tunnels
Fingers
Aptitude
Touch
Weights and Measures
torque
Modulation
central nervous system
Feedback
hands
texture
Force control
Torque
Neurology

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Zhang, W., Johnston, J. A., Ross, M. A., Sanniec, K., Gleason, E. A., Dueck, A. C., & Santello, M. (2013). Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent. PLoS One, 8(1), [e53751]. https://doi.org/10.1371/journal.pone.0053751

Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent. / Zhang, Wei; Johnston, Jamie A.; Ross, Mark A.; Sanniec, Kyle; Gleason, Elizabeth A.; Dueck, Amylou C.; Santello, Marco.

In: PLoS One, Vol. 8, No. 1, e53751, 17.01.2013.

Research output: Contribution to journalArticle

Zhang, W, Johnston, JA, Ross, MA, Sanniec, K, Gleason, EA, Dueck, AC & Santello, M 2013, 'Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent', PLoS One, vol. 8, no. 1, e53751. https://doi.org/10.1371/journal.pone.0053751
Zhang W, Johnston JA, Ross MA, Sanniec K, Gleason EA, Dueck AC et al. Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent. PLoS One. 2013 Jan 17;8(1). e53751. https://doi.org/10.1371/journal.pone.0053751
Zhang, Wei ; Johnston, Jamie A. ; Ross, Mark A. ; Sanniec, Kyle ; Gleason, Elizabeth A. ; Dueck, Amylou C. ; Santello, Marco. / Effects of Carpal Tunnel Syndrome on Dexterous Manipulation Are Grip Type-Dependent. In: PLoS One. 2013 ; Vol. 8, No. 1.
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