Effect of pathogen-resistant vectors on the transmission dynamics of a vector-borne disease

Julien Arino, Chris Bowman, Abba Gumel, Stéphanie Portet

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A model is introduced for the transmission dynamics of a vector-borne disease with two vector strains, one wild and one pathogen-resistant; resistance comes at the cost of reduced reproductive fitness. The model, which assumes that vector reproduction can lead to the transmission or loss of resistance (reversion), is analyzed in a particular case with specified forms for the birth and force of infection functions. The vector component can have, in the absence of disease, a coexistence equilibrium where both strains survive. In the case where reversion is possible, this coexistence equilibrium is globally asymptotically stable when it exists. This equilibrium is still present in the full vector–host system, leading to a reduction of the associated reproduction number, thereby making elimination of the disease more feasible. When reversion is not possible, there can exist an additional equilibrium with only resistant vectors.

Original languageEnglish (US)
Pages (from-to)320-346
Number of pages27
JournalJournal of biological dynamics
Volume1
Issue number4
DOIs
StatePublished - Oct 2007
Externally publishedYes

Keywords

  • Multiple disease-free equilibria
  • Pair formation
  • Vector–host disease

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology

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