TY - JOUR
T1 - Effect of nopales (Opuntia spp.) on lipoprotein profile and oxidative stress among moderately hypercholesterolemic adults
T2 - A pilot study
AU - Pignotti, G. A P
AU - Hook, G.
AU - Ghan, E.
AU - Vega-Lopez, Sonia
N1 - Funding Information:
The authors want to thank study participants for their contributions to this study. Data were collected with support from the Arizona Board of Regents (ABOR) Doctoral Research Grant and Arizona State University Graduate Research Support Program Grant. The funding sources had no involvement in the study design, data collection, analysis and interpretation, writing of the report, and decision to submit the article for publication.
Publisher Copyright:
© 2016
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - This study evaluated the effect of nopales (prickly pear cactus pads) for improving cardiometabolic risk factors and oxidative stress, compared to control, in hypercholesterolemic adults. In a randomized crossover trial, participants were assigned to a 2-wk intervention with 2 cups/day of nopales or cucumbers (control), with a 2 to 3-wk washout period. The study included 16 adults (46 ± 14 y; BMI = 31.4 ± 5.7 kg/m2) with moderate hypercholesterolemia. There was no significant treatment-by-time effect for any dietary composition data, lipid profile, cardiometabolic outcomes, or oxidative stress markers. Both treatments significantly increased triglyceride concentrations (cucumber, 14.8%; nopales, 15.2%; pTime = 0.020). On average, LDL-c was decreased by 2.0 mg/dL (−1.4%) after the cucumber phase and 3.9 mg/dL (−2.9%) after the nopales phase (pTime = 0.176). In conclusion, these data do not support the purported benefits of nopales at doses of 2 cups/day for 2-wk on markers of lipoprotein profile, cardiometabolic risk, and oxidative stress in hypercholesterolemic adults.
AB - This study evaluated the effect of nopales (prickly pear cactus pads) for improving cardiometabolic risk factors and oxidative stress, compared to control, in hypercholesterolemic adults. In a randomized crossover trial, participants were assigned to a 2-wk intervention with 2 cups/day of nopales or cucumbers (control), with a 2 to 3-wk washout period. The study included 16 adults (46 ± 14 y; BMI = 31.4 ± 5.7 kg/m2) with moderate hypercholesterolemia. There was no significant treatment-by-time effect for any dietary composition data, lipid profile, cardiometabolic outcomes, or oxidative stress markers. Both treatments significantly increased triglyceride concentrations (cucumber, 14.8%; nopales, 15.2%; pTime = 0.020). On average, LDL-c was decreased by 2.0 mg/dL (−1.4%) after the cucumber phase and 3.9 mg/dL (−2.9%) after the nopales phase (pTime = 0.176). In conclusion, these data do not support the purported benefits of nopales at doses of 2 cups/day for 2-wk on markers of lipoprotein profile, cardiometabolic risk, and oxidative stress in hypercholesterolemic adults.
KW - Cardiometabolic risk
KW - Functional food
KW - Lipoprotein profile
KW - Nopales
KW - Oxidative stress
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U2 - 10.1016/j.jff.2016.08.060
DO - 10.1016/j.jff.2016.08.060
M3 - Article
AN - SCOPUS:84988384749
SN - 1756-4646
VL - 27
SP - 115
EP - 121
JO - Journal of Functional Foods
JF - Journal of Functional Foods
ER -