Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase 11 gene expression in human leukemia cells

Leonard A. Zwelling; Diana Chan; Elizabeth Altschuler; Janice Mayes; Michael Hinds; George Pettit

doi:10.1016/0006-2952(91)90087-L

Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase 11 gene expression in human leukemia cells

Leonard A. Zwelling, Diana Chan, Elizabeth Altschuler, Janice Mayes, Michael Hinds, George Pettit

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	829-832
Number of pages	4
Journal	Biochemical Pharmacology
Volume	41
Issue number	5
DOIs	https://doi.org/10.1016/0006-2952(91)90087-L
State	Published - Mar 1 1991

ASJC Scopus subject areas

Biochemistry
Pharmacology

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10.1016/0006-2952(91)90087-L

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title = "Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase 11 gene expression in human leukemia cells",

author = "Zwelling, {Leonard A.} and Diana Chan and Elizabeth Altschuler and Janice Mayes and Michael Hinds and George Pettit",

note = "Funding Information: Acknowledgement+-Thisw ork was supported by PHS Research Grant CA40090, Grant CH-324C from the American Cancer Society, and a contributionf rom the NucleoporeC orporation of Pleasanton,C A, to L.A.Z., and by the Fannie E. Rippel Foundation, the Arizona DiseaseC ontrol ResearchC ommission,t he Robert B. Dalton Endowment Fund, and an OutstandingI nvestigator Grant CA-44344-OlAl (NCI, DHHS) to G.R.P. We thank Dr. Robert Hall of the Guthrie ResearchI nstitute,S ayre, PA, for providing the HL-60 cells; Dr. Leroy Liu of the Johns Hopkins Schoolo f Medicine for his gift of the human cDNA topoisomeraseII genep robe;D r. Mark Blick of the M.D. Anderson Cancer Center for supplyingt he c-myc probe; Dr. Cherry L. Herald for other assistance;a nd Diane Rivera for editing the manuscript.",

year = "1991",

month = mar,

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doi = "10.1016/0006-2952(91)90087-L",

language = "English (US)",

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T1 - Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase 11 gene expression in human leukemia cells

AU - Zwelling, Leonard A.

AU - Chan, Diana

AU - Altschuler, Elizabeth

AU - Mayes, Janice

AU - Hinds, Michael

AU - Pettit, George

N1 - Funding Information: Acknowledgement+-Thisw ork was supported by PHS Research Grant CA40090, Grant CH-324C from the American Cancer Society, and a contributionf rom the NucleoporeC orporation of Pleasanton,C A, to L.A.Z., and by the Fannie E. Rippel Foundation, the Arizona DiseaseC ontrol ResearchC ommission,t he Robert B. Dalton Endowment Fund, and an OutstandingI nvestigator Grant CA-44344-OlAl (NCI, DHHS) to G.R.P. We thank Dr. Robert Hall of the Guthrie ResearchI nstitute,S ayre, PA, for providing the HL-60 cells; Dr. Leroy Liu of the Johns Hopkins Schoolo f Medicine for his gift of the human cDNA topoisomeraseII genep robe;D r. Mark Blick of the M.D. Anderson Cancer Center for supplyingt he c-myc probe; Dr. Cherry L. Herald for other assistance;a nd Diane Rivera for editing the manuscript.

PY - 1991/3/1

Y1 - 1991/3/1

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JO - Biochemical Pharmacology

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Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase 11 gene expression in human leukemia cells

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