The need for multi-component vaccines that are inexpensive, orally delivered and stable might be met by using plants to express recombinant vaccine genes. Bacterial and viral diarrhoeal diseases are likely targets for such 'edible' vaccines, because their surface antigens are stable in the gut. Furthermore, antibodies secreted into the gut in response to antigen stimulation are well positioned to fight diarrhoeal infections. Animal studies show that such antibodies can be produced, and clinical studies will determine whether they can be produced in humans by similar means.
|Original language||English (US)|
|Number of pages||3|
|Journal||Vaccines: Children and Practice|
|State||Published - Dec 1 1998|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health