TY - JOUR
T1 - Dynamically modulated intensity interrogation scheme using waveguide coupled surface plasmon resonance sensors
AU - Ma, Xin
AU - Xu, Xinlong
AU - Zheng, Zheng
AU - Wang, Kun
AU - Su, Yalin
AU - Fan, Jiangfeng
AU - Zhang, Rui
AU - Song, Lusheng
AU - Wang, Zhiyou
AU - Zhu, Jinsong
N1 - Funding Information:
This work was supported by 973 Program (2009CB930702), and the work at Beihang University was also partially supported by NSFC (60877054), NCET and PCSIRT, SEM. The authors acknowledge the help from Zhanglei Wang from Beijing Institute of Technology on sensor chip fabrication. Sincere thanks are due to Prof. Jim Diamond from Linfield College for many helpful suggestions and comments on the manuscript.
Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/1
Y1 - 2010/1
N2 - An electro-optically modulated intensity interrogation method based on tunable waveguide coupled surface plasmon resonance sensors has been proposed. It has been theoretically and experimentally demonstrated that the proposed scheme can enable sensitive measurement of measurand variations. By modulating the refractive index in the waveguide layer, this interrogation method yields modulated signal whose amplitude is related to measurand's refractive index. This amplitude modulated signal offers a higher signal to noise ratio and eliminates additive noise in the sensor system. A preliminary investigation using saline buffers with different NaCl concentrations shows a resolution of 2.3 × 10-6 refractive index unit by our approach. Resolution can be controlled by the amplitude of the applied modulation voltage and can be further enhanced by optimizing the device structure or improving the electro-optical (E-O) coefficient of the E-O material. This approach is simple, stable, and promising for low-cost or multi-channel SPR biosensor applications.
AB - An electro-optically modulated intensity interrogation method based on tunable waveguide coupled surface plasmon resonance sensors has been proposed. It has been theoretically and experimentally demonstrated that the proposed scheme can enable sensitive measurement of measurand variations. By modulating the refractive index in the waveguide layer, this interrogation method yields modulated signal whose amplitude is related to measurand's refractive index. This amplitude modulated signal offers a higher signal to noise ratio and eliminates additive noise in the sensor system. A preliminary investigation using saline buffers with different NaCl concentrations shows a resolution of 2.3 × 10-6 refractive index unit by our approach. Resolution can be controlled by the amplitude of the applied modulation voltage and can be further enhanced by optimizing the device structure or improving the electro-optical (E-O) coefficient of the E-O material. This approach is simple, stable, and promising for low-cost or multi-channel SPR biosensor applications.
KW - Modulation
KW - Optical sensing and sensors
KW - Polymer active device
KW - Surface plasmon
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U2 - 10.1016/j.sna.2009.11.004
DO - 10.1016/j.sna.2009.11.004
M3 - Article
AN - SCOPUS:76649121182
SN - 0924-4247
VL - 157
SP - 9
EP - 14
JO - Sensors and Actuators, A: Physical
JF - Sensors and Actuators, A: Physical
IS - 1
ER -