In Service-Oriented Architecture (SOA) and Service-Oriented Computing (SOC), service collaboration is an important aspect. While service collaboration protocols for data exchange are well explored, the Dynamic Process Collaboration (DPC) is still a challenging issue. The DPC brings new features and uncertainty to the current SOA/SOC, such as run-time behavior evaluation, dynamic collaboration performance measurement and dynamic Recomposition/ Reconfiguration capability assessment. This paper presents the Dynamic Service-Oriented Collaboration Simulation (DSOCS) framework we have developed, which supports the dynamic collaboration, development, simulation, and evaluation of large scale SOA systems. The distinct features of the framework include automated simulation code generation from the specification, code deployment, and simulation of different architectures with a template-based platform builder, service-oriented multi-agent simulation for easy reconfiguration, and dynamic analyses of results from evaluation and monitoring. The framework and the associated tools have been implemented and applied in several governmental and industrial projects.