Drug delivery applications of injectable biomaterials

D. J. Overstreet, H. A. Von Recum, Brent Vernon

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter discusses the design and applications of injectable biomaterials for the controlled delivery of drugs, proteins, and other therapeutics for the treatment of various diseases. The first half of the chapter describes in situ forming drug delivery systems which are injectable as a liquid, forming a solid or semi-solid depot after injection which then releases the drug. The second half of the chapter discusses particulate drug delivery systems which are often injected into the circulation. Emphasis is placed on clinical applications as well as stimuli responsive and/or targeted drug delivery. Design choices relevant to each class of injectable system are highlighted.

Original languageEnglish (US)
Title of host publicationInjectable Biomaterials
Subtitle of host publicationScience and Applications
PublisherElsevier Inc.
Pages95-141
Number of pages47
ISBN (Print)9781845695880
DOIs
StatePublished - Jan 1 2011

Keywords

  • Drug delivery
  • Injectable drug depot
  • Nanoparticles
  • Targeted cancer chemotherapy

ASJC Scopus subject areas

  • Materials Science(all)

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