Drug delivery applications of injectable biomaterials

D. J. Overstreet, H. A. Von Recum, Brent Vernon

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter discusses the design and applications of injectable biomaterials for the controlled delivery of drugs, proteins, and other therapeutics for the treatment of various diseases. The first half of the chapter describes in situ forming drug delivery systems which are injectable as a liquid, forming a solid or semi-solid depot after injection which then releases the drug. The second half of the chapter discusses particulate drug delivery systems which are often injected into the circulation. Emphasis is placed on clinical applications as well as stimuli responsive and/or targeted drug delivery. Design choices relevant to each class of injectable system are highlighted.

Original languageEnglish (US)
Title of host publicationInjectable Biomaterials: Science and Applications
PublisherElsevier Inc.
Pages95-141
Number of pages47
ISBN (Print)9781845695880
DOIs
StatePublished - Jan 2011

Fingerprint

Biocompatible Materials
Drug delivery
Biomaterials
Pharmaceutical Preparations
Proteins
Liquids
Drug Delivery Systems
Targeted drug delivery

Keywords

  • Drug delivery
  • Injectable drug depot
  • Nanoparticles
  • Targeted cancer chemotherapy

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Overstreet, D. J., Von Recum, H. A., & Vernon, B. (2011). Drug delivery applications of injectable biomaterials. In Injectable Biomaterials: Science and Applications (pp. 95-141). Elsevier Inc.. https://doi.org/10.1016/B978-1-84569-588-0.50005-X

Drug delivery applications of injectable biomaterials. / Overstreet, D. J.; Von Recum, H. A.; Vernon, Brent.

Injectable Biomaterials: Science and Applications. Elsevier Inc., 2011. p. 95-141.

Research output: Chapter in Book/Report/Conference proceedingChapter

Overstreet, DJ, Von Recum, HA & Vernon, B 2011, Drug delivery applications of injectable biomaterials. in Injectable Biomaterials: Science and Applications. Elsevier Inc., pp. 95-141. https://doi.org/10.1016/B978-1-84569-588-0.50005-X
Overstreet DJ, Von Recum HA, Vernon B. Drug delivery applications of injectable biomaterials. In Injectable Biomaterials: Science and Applications. Elsevier Inc. 2011. p. 95-141 https://doi.org/10.1016/B978-1-84569-588-0.50005-X
Overstreet, D. J. ; Von Recum, H. A. ; Vernon, Brent. / Drug delivery applications of injectable biomaterials. Injectable Biomaterials: Science and Applications. Elsevier Inc., 2011. pp. 95-141
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