Drug delivery applications of injectable biomaterials

D. J. Overstreet; H. A. Von Recum; Brent Vernon

doi:10.1016/B978-1-84569-588-0.50005-X

Drug delivery applications of injectable biomaterials

D. J. Overstreet, H. A. Von Recum, Brent Vernon

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

This chapter discusses the design and applications of injectable biomaterials for the controlled delivery of drugs, proteins, and other therapeutics for the treatment of various diseases. The first half of the chapter describes in situ forming drug delivery systems which are injectable as a liquid, forming a solid or semi-solid depot after injection which then releases the drug. The second half of the chapter discusses particulate drug delivery systems which are often injected into the circulation. Emphasis is placed on clinical applications as well as stimuli responsive and/or targeted drug delivery. Design choices relevant to each class of injectable system are highlighted.

Original language	English (US)
Title of host publication	Injectable Biomaterials
Subtitle of host publication	Science and Applications
Publisher	Elsevier Inc.
Pages	95-141
Number of pages	47
ISBN (Print)	9781845695880
DOIs	https://doi.org/10.1016/B978-1-84569-588-0.50005-X
State	Published - Jan 2011

Keywords

Drug delivery
Injectable drug depot
Nanoparticles
Targeted cancer chemotherapy

ASJC Scopus subject areas

General Materials Science

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10.1016/B978-1-84569-588-0.50005-X

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AB - This chapter discusses the design and applications of injectable biomaterials for the controlled delivery of drugs, proteins, and other therapeutics for the treatment of various diseases. The first half of the chapter describes in situ forming drug delivery systems which are injectable as a liquid, forming a solid or semi-solid depot after injection which then releases the drug. The second half of the chapter discusses particulate drug delivery systems which are often injected into the circulation. Emphasis is placed on clinical applications as well as stimuli responsive and/or targeted drug delivery. Design choices relevant to each class of injectable system are highlighted.

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Drug delivery applications of injectable biomaterials

Abstract

Keywords

ASJC Scopus subject areas

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