DNA-templated self-assembly of protein arrays and highly conductive nanowires

Hao Yan, Sung Ha Park, Gleb Finkelstein, John H. Reif, Thomas H. LaBean

Research output: Contribution to journalArticle

1360 Scopus citations

Abstract

A DNA nanostructure consisting of four four-arm junctions oriented with a square aspect ratio was designed and constructed. Programmable self-assembly of 4 × 4 tiles resulted in two distinct lattice morphologies: uniform-width nanoribbons and two-dimensional nanogrids, which both display periodic square cavities. Periodic protein arrays were achieved by templated self-assembly of streptavidin onto the DNA nanogrids containing biotinylated oligonucleotides. On the basis of a two-step metallization procedure, the 4 × 4 nanoribbons acted as an excellent scaffold for the production of highly conductive, uniform-width, silver nanowires.

Original languageEnglish (US)
Pages (from-to)1882-1884
Number of pages3
JournalScience
Volume301
Issue number5641
DOIs
Publication statusPublished - Sep 26 2003
Externally publishedYes

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Cite this

Yan, H., Park, S. H., Finkelstein, G., Reif, J. H., & LaBean, T. H. (2003). DNA-templated self-assembly of protein arrays and highly conductive nanowires. Science, 301(5641), 1882-1884. https://doi.org/10.1126/science.1089389