Abstract

As common engineered nanomaterials, TiO2 nanoparticles (nTiO2) are usually perceived as non-toxic, and have already been widely used in many products and applications. Such a perception might have been shaped by some short-term studies that revealed no/low toxicity of nTiO2 to cells and eco-relevant organisms. However, given the ultimate release of nTiO2 into the aquatic environment, which can act as a sink for engineered nanoparticles, their long-term impact on the environment and human health is still a concern and deserves more research efforts. Here, for the first time, we demonstrate that chronic exposure of zebrafish to 0.1mgL-1 nTiO2, can significantly impair zebrafish reproduction. For instance, there was a 29.5% reduction in the cumulative number of zebrafish eggs after 13weeks of nTiO2 exposure. Thus, we provided timely information on indicating a serious risk of reproductive impairment of environments contaminated with low levels of nTiO2 on aquatic organisms, leading to alterations in population dynamics and aquatic ecosystem balance, and thus warrants a careful scrutiny on toxicity assessment of nTiO2, especially their long-term impact.

Original languageEnglish (US)
Pages (from-to)461-467
Number of pages7
JournalChemosphere
Volume83
Issue number4
DOIs
StatePublished - Apr 2011

Fingerprint

Zebrafish
Nanostructures
Nanoparticles
Reproduction
Nanostructured materials
Toxicity
toxicity
Aquatic organisms
Aquatic Organisms
Population dynamics
Aquatic ecosystems
exposure
nanoparticle
Population Dynamics
aquatic organism
aquatic ecosystem
aquatic environment
Eggs
Ecosystem
population dynamics

Keywords

  • Acute toxicity
  • Bioaccumulation
  • Chronic toxicity
  • Microarry
  • Nanoparticles
  • Reproduction
  • TiO
  • Zebrafish

ASJC Scopus subject areas

  • Environmental Chemistry
  • Chemistry(all)

Cite this

Disruption of zebrafish (Danio rerio) reproduction upon chronic exposure to TiO2 nanoparticles. / Wang, Jiangxin; Zhu, Xiaoshan; Zhang, Xuezhi; Zhao, Zheng; Liu, Huan; George, Rajani; Wilson-Rawls, Norma; Chang, Yung; Chen, Yongsheng.

In: Chemosphere, Vol. 83, No. 4, 04.2011, p. 461-467.

Research output: Contribution to journalArticle

Wang, Jiangxin ; Zhu, Xiaoshan ; Zhang, Xuezhi ; Zhao, Zheng ; Liu, Huan ; George, Rajani ; Wilson-Rawls, Norma ; Chang, Yung ; Chen, Yongsheng. / Disruption of zebrafish (Danio rerio) reproduction upon chronic exposure to TiO2 nanoparticles. In: Chemosphere. 2011 ; Vol. 83, No. 4. pp. 461-467.
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