Disposable point-of-use optical biosensor for multiple biomarker detection

Joseph T. Smith, Benjamin A. Katchman, Yong Kyun Lee, Barry P. O'Brien, Edward J. Bawolek, Sahil S. Shah, Jennifer Blain Christen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

This work explored the viability of a new miniaturized fluorescence measurement-based sensor architecture using organic light emitting diode (OLED) display and photodiode active matrix array technology for point-of-use diagnosis of multiple disease biomarkers in a low cost disposable configuration. Sensor feasibility and optical performance were evaluated using a bright 0.3mW/mm2 2 × 2 mm, 455nm blue OLED emitter test structure configured first with orthogonally crossed linear polarizing film; and second, with band-pass and long-pass optical filters. Preliminary measurement results indicated that this type of sensor architecture requires optical filters to approach the sensitivity of laboratory fluorescence-based instrumentation.

Original languageEnglish (US)
Title of host publicationIEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages268-271
Number of pages4
ISBN (Electronic)9781479923465
DOIs
StatePublished - Dec 9 2014
Event10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014 - Lausanne, Switzerland
Duration: Oct 22 2014Oct 24 2014

Publication series

NameIEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings

Other

Other10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014
CountrySwitzerland
CityLausanne
Period10/22/1410/24/14

    Fingerprint

Keywords

  • Biomarker
  • OLED
  • TFT
  • Thin-film transistor
  • active matrix array
  • biosensor
  • photodiode
  • point-of-care

ASJC Scopus subject areas

  • Hardware and Architecture
  • Biomedical Engineering

Cite this

Smith, J. T., Katchman, B. A., Lee, Y. K., O'Brien, B. P., Bawolek, E. J., Shah, S. S., & Blain Christen, J. (2014). Disposable point-of-use optical biosensor for multiple biomarker detection. In IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings (pp. 268-271). [6981714] (IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS.2014.6981714