Direct measurement of capillary blood pressure in the human lip

S. E. Parazynski, B. J. Tucker, M. Aratow, A. Crenshaw, A. R. Hargens

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In this study, we developed and tested a new procedure for measuring microcirculatory blood pressures above heart level in humans. Capillary and postcapillary venule blood pressures were measured directly in 13 human subjects by use of the servo-nulling micropressure technique adapted for micropuncture of lip capillaries. Pressure waveforms were recorded in 40 separate capillary vessels and 14 separate postcapillary venules over periods ranging from 5 to 64 s. Localization and determination of capillary and postcapillary vessels were ascertained anatomically before pressure measurements. Capillary pressure was 33.2 ± 1.5 (SE) mmHg in lips of subjects seated upright. Repeated micropunctures of the same vessel gave an average coefficient of variation of 0.072. Postcapillary venule pressure was 18.9 ± 1.6 mmHg. This procedure produces a direct and reproducible means of measuring microvascular blood pressures in a vascular bed above heart level in humans.

Original languageEnglish (US)
Pages (from-to)946-950
Number of pages5
JournalJournal of Applied Physiology
Volume74
Issue number2
StatePublished - 1993
Externally publishedYes

Fingerprint

Lip
Venules
Blood Pressure
Pressure
Punctures
Blood Vessels

Keywords

  • microcirculation
  • micropipette
  • micropressures
  • postcapillary venule pressure
  • servo-nulling technique

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Parazynski, S. E., Tucker, B. J., Aratow, M., Crenshaw, A., & Hargens, A. R. (1993). Direct measurement of capillary blood pressure in the human lip. Journal of Applied Physiology, 74(2), 946-950.

Direct measurement of capillary blood pressure in the human lip. / Parazynski, S. E.; Tucker, B. J.; Aratow, M.; Crenshaw, A.; Hargens, A. R.

In: Journal of Applied Physiology, Vol. 74, No. 2, 1993, p. 946-950.

Research output: Contribution to journalArticle

Parazynski, SE, Tucker, BJ, Aratow, M, Crenshaw, A & Hargens, AR 1993, 'Direct measurement of capillary blood pressure in the human lip', Journal of Applied Physiology, vol. 74, no. 2, pp. 946-950.
Parazynski SE, Tucker BJ, Aratow M, Crenshaw A, Hargens AR. Direct measurement of capillary blood pressure in the human lip. Journal of Applied Physiology. 1993;74(2):946-950.
Parazynski, S. E. ; Tucker, B. J. ; Aratow, M. ; Crenshaw, A. ; Hargens, A. R. / Direct measurement of capillary blood pressure in the human lip. In: Journal of Applied Physiology. 1993 ; Vol. 74, No. 2. pp. 946-950.
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