Different activation of immune-related genes in honey bee nurses and foragers (Apis mellifera)

Eva Marit Hystad Byhrø, Heli Salmela, Ana Vitlic, Ying Wang, Daniel Münch, Gro V. Amdam

Research output: Contribution to journalArticle

Abstract

Honey bee workers show very flexible aging patterns. Their typical behavioral progression, from nurse bees to forager bees, is associated with an onset of aging symptoms. Here, we studied how immune-activation can affect nurse and forager bees differently. Nurse and forager bees of identical chronological age were injected with vehicle control or the bacterial cell wall components lipopolysaccharide (LPS) or peptidoglycan (PGN). Next, we monitored survival and tested the expression of three immune-related genes. We confirm that forager bees die sooner than same-aged nurse bees, independent of the type of immune challenge. The relative gene expression patterns of two immune-related genes differed between the nurse and forager honey bees as well as between the treatment groups. Our findings support that nurse and forager honey bees can respond differently to immune challenge, despite a lack of detectable differences in mortality between treatments. This response was specifically associated with the workers’ behavioral caste, as the chronological age was similar among all tested animals.

Original languageEnglish (US)
Pages (from-to)463-471
Number of pages9
JournalApidologie
Volume50
Issue number4
DOIs
StatePublished - Aug 15 2019

Keywords

  • aging
  • defensin-2
  • honeybee
  • immune activation
  • vitellogenin

ASJC Scopus subject areas

  • Insect Science

Fingerprint Dive into the research topics of 'Different activation of immune-related genes in honey bee nurses and foragers (Apis mellifera)'. Together they form a unique fingerprint.

  • Cite this