Development of quantitative mass spectrometric immunoassay for serum amyloid A

Olgica Trenchevska, Hussein N. Yassine, Chad Borges, Randall W. Nelson, Dobrin Nedelkov

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: Proteins can exist as multiple proteoforms in vivo that can have important roles in physiological and pathological states. Methods: We present the development and characterization of mass spectrometric immunoassay (MSIA) for quantitative determination of serum amyloid A (SAA) proteoforms. Results: Intra- and inter-day precision revealed CVs

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalBiomarkers
DOIs
StateAccepted/In press - Jul 22 2016

Fingerprint

Serum Amyloid A Protein
Immunoassay
Proteins

Keywords

  • Baseline concentration
  • inflammation biomarker
  • mass spectrometry
  • polymorphism
  • posttranslational modifications
  • proteoforms

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Health, Toxicology and Mutagenesis

Cite this

Development of quantitative mass spectrometric immunoassay for serum amyloid A. / Trenchevska, Olgica; Yassine, Hussein N.; Borges, Chad; Nelson, Randall W.; Nedelkov, Dobrin.

In: Biomarkers, 22.07.2016, p. 1-9.

Research output: Contribution to journalArticle

Trenchevska, Olgica ; Yassine, Hussein N. ; Borges, Chad ; Nelson, Randall W. ; Nedelkov, Dobrin. / Development of quantitative mass spectrometric immunoassay for serum amyloid A. In: Biomarkers. 2016 ; pp. 1-9.
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