Development of quantitative mass spectrometric immunoassay for serum amyloid A

Olgica Trenchevska, Hussein N. Yassine, Chad Borges, Randall W. Nelson, Dobrin Nedelkov

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Objective: Proteins can exist as multiple proteoforms in vivo that can have important roles in physiological and pathological states. Methods: We present the development and characterization of mass spectrometric immunoassay (MSIA) for quantitative determination of serum amyloid A (SAA) proteoforms. Results: Intra- and inter-day precision revealed CVs

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalBiomarkers
DOIs
StateAccepted/In press - Jul 22 2016

Keywords

  • Baseline concentration
  • inflammation biomarker
  • mass spectrometry
  • polymorphism
  • posttranslational modifications
  • proteoforms

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Health, Toxicology and Mutagenesis

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