Detection of hematoporphyrin fluorescence during fiberoptic bronchoscopy to localize early bronchogenic carcinoma

J. H. Kinsey, D. A. Cortese, D. R. Sanderson

Research output: Contribution to journalArticlepeer-review

75 Scopus citations

Abstract

Photoelectric detection of fluorescence from hematoporphyrin-containing 'occult' bronchogenic carcinoma is a potentially useful technique for localizing and delineating such cancers. A method is presented which would enable use of a fluorescence-detection system simultaneously with conventional illumination during flexible bronchofiberscopic examination. Preliminary data suggest that quantities of hematoporphyrin as small as 5 picograms can be detected on the surface of tumors by this method.

Original languageEnglish (US)
Pages (from-to)594-600
Number of pages7
JournalMayo Clinic Proceedings
Volume53
Issue number9
StatePublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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