Design Principles of the Rotary Type 9 Secretion System

Abhishek Trivedi; Jitendrapuri Gosai; Daisuke Nakane; Abhishek Shrivastava

doi:10.3389/fmicb.2022.845563

Design Principles of the Rotary Type 9 Secretion System

Abhishek Trivedi, Jitendrapuri Gosai, Daisuke Nakane, Abhishek Shrivastava

Life Sciences, School of (SOLS)

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

The F_o ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism via which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.

Original language	English (US)
Article number	845563
Journal	Frontiers in Microbiology
Volume	13
DOIs	https://doi.org/10.3389/fmicb.2022.845563
State	Published - May 10 2022

Keywords

Flavobacteria
T9SS
bacterial motility
bacterial swarming
gliding motility

ASJC Scopus subject areas

Microbiology
Microbiology (medical)

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10.3389/fmicb.2022.845563

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title = "Design Principles of the Rotary Type 9 Secretion System",

abstract = "The Fo ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism via which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.",

keywords = "Flavobacteria, T9SS, bacterial motility, bacterial swarming, gliding motility",

author = "Abhishek Trivedi and Jitendrapuri Gosai and Daisuke Nakane and Abhishek Shrivastava",

note = "Funding Information: AS was supported by NIH grant DE026826. Publisher Copyright: Copyright {\textcopyright} 2022 Trivedi, Gosai, Nakane and Shrivastava.",

year = "2022",

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doi = "10.3389/fmicb.2022.845563",

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T1 - Design Principles of the Rotary Type 9 Secretion System

AU - Trivedi, Abhishek

AU - Gosai, Jitendrapuri

AU - Nakane, Daisuke

AU - Shrivastava, Abhishek

PY - 2022/5/10

Y1 - 2022/5/10

N2 - The Fo ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism via which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.

AB - The Fo ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism via which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.

KW - Flavobacteria

KW - T9SS

KW - bacterial motility

KW - bacterial swarming

KW - gliding motility

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DO - 10.3389/fmicb.2022.845563

M3 - Review article

AN - SCOPUS:85130717892

SN - 1664-302X

VL - 13

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

M1 - 845563

ER -

Design Principles of the Rotary Type 9 Secretion System

Abstract

Keywords

ASJC Scopus subject areas

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