Design of membrane proteins: toward functional systems

Giovanna Ghirlanda

doi:10.1016/j.cbpa.2009.09.017

Design of membrane proteins: toward functional systems

Giovanna Ghirlanda

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Over the years, membrane-soluble peptides have provided a convenient model system to investigate the folding and assembly of integral membrane proteins. Recent advances in experimental and computational methods are now being translated into the design of functional membrane proteins. Applications include artificial modulators of membrane protein function, inhibitors of protein-protein interactions, and redox membrane proteins.

Original language	English (US)
Pages (from-to)	643-651
Number of pages	9
Journal	Current Opinion in Chemical Biology
Volume	13
Issue number	5-6
DOIs	https://doi.org/10.1016/j.cbpa.2009.09.017
State	Published - Dec 1 2009

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry

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abstract = "Over the years, membrane-soluble peptides have provided a convenient model system to investigate the folding and assembly of integral membrane proteins. Recent advances in experimental and computational methods are now being translated into the design of functional membrane proteins. Applications include artificial modulators of membrane protein function, inhibitors of protein-protein interactions, and redox membrane proteins.",

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