Depressive Symptoms During Childhood and Cardiovascular Risk Factors in Black and White Men

Karen A. Matthews, J. Richard Jennings, Laisze Lee, Dustin Pardini

Research output: Contribution to journalArticle

Abstract

Objective Depressive symptoms and major depression predict cardiovascular disease (CVD) and CVD risk factors in adulthood. Evidence regarding the role of depression in the development of CVD risk in youth is minimal. The study evaluated the prospective relationship of depressive symptoms in childhood and adolescence with adult CVD risk factors in black and white men. Methods Health behaviors and medical history were measured in 165 black and 146 white men (mean age = 32); a subset in the Pittsburgh area had a fasting blood draw to measure metabolic syndrome and inflammation. Adult CVD risk factors were related to depressive symptoms and childhood socioeconomic status (SES) prospectively measured annually from ages 7 to 16 years, followed by adjustments for adult SES and depressive symptoms. Results Men with higher depressive symptoms ages 7 to 16 smoked more cigarettes, B = 0.28 (standard error = 0.12), p =.015, and ate fewer servings of fruits and vegetables, B = -0.08 (0.04), p =.040, as adults. The association for smoking was independent of adult depressive symptoms (concurrent) and childhood and adult SES as well as race. Depressive symptoms during childhood were unrelated to the metabolic syndrome or biomarkers of inflammation in adulthood. Conclusions Depressive symptoms in childhood may predict later adverse health behaviors in black and white men. No evidence was found for an association between childhood depressive symptoms with metabolic syndrome or inflammation markers at ages approximately 32 years. The nature of the sample and lack of measurement of depressive disorder diagnosis tempers the conclusions, and future research is needed to determine associations with biological measures at later life span phases.

Original languageEnglish (US)
Pages (from-to)176-183
Number of pages8
JournalPsychosomatic Medicine
Volume81
Issue number2
DOIs
StatePublished - Feb 1 2019

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Depression
Cardiovascular Diseases
Social Class
Health Behavior
Inflammation
hydroquinone
Depressive Disorder
Tobacco Products
Vegetables
Fasting
Fruit
Biomarkers
Smoking
Prospective Studies

Keywords

  • BMI = body mass index
  • cigarette smoking
  • CRP = C-reactive protein
  • CVD = cardiovascular disease
  • DBP = diastolic blood pressure
  • depression
  • HDL-C = high density lipoprotein-cholesterol
  • health behaviors
  • IL-6 = interleukin 6
  • inflammation
  • longitudinal
  • men
  • metabolic syndrome
  • PYS = Pittsburgh Youth Study
  • race
  • SBP = systolic blood pressure
  • SES = socioeconomic status

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health

Cite this

Depressive Symptoms During Childhood and Cardiovascular Risk Factors in Black and White Men. / Matthews, Karen A.; Jennings, J. Richard; Lee, Laisze; Pardini, Dustin.

In: Psychosomatic Medicine, Vol. 81, No. 2, 01.02.2019, p. 176-183.

Research output: Contribution to journalArticle

Matthews, Karen A. ; Jennings, J. Richard ; Lee, Laisze ; Pardini, Dustin. / Depressive Symptoms During Childhood and Cardiovascular Risk Factors in Black and White Men. In: Psychosomatic Medicine. 2019 ; Vol. 81, No. 2. pp. 176-183.
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abstract = "Objective Depressive symptoms and major depression predict cardiovascular disease (CVD) and CVD risk factors in adulthood. Evidence regarding the role of depression in the development of CVD risk in youth is minimal. The study evaluated the prospective relationship of depressive symptoms in childhood and adolescence with adult CVD risk factors in black and white men. Methods Health behaviors and medical history were measured in 165 black and 146 white men (mean age = 32); a subset in the Pittsburgh area had a fasting blood draw to measure metabolic syndrome and inflammation. Adult CVD risk factors were related to depressive symptoms and childhood socioeconomic status (SES) prospectively measured annually from ages 7 to 16 years, followed by adjustments for adult SES and depressive symptoms. Results Men with higher depressive symptoms ages 7 to 16 smoked more cigarettes, B = 0.28 (standard error = 0.12), p =.015, and ate fewer servings of fruits and vegetables, B = -0.08 (0.04), p =.040, as adults. The association for smoking was independent of adult depressive symptoms (concurrent) and childhood and adult SES as well as race. Depressive symptoms during childhood were unrelated to the metabolic syndrome or biomarkers of inflammation in adulthood. Conclusions Depressive symptoms in childhood may predict later adverse health behaviors in black and white men. No evidence was found for an association between childhood depressive symptoms with metabolic syndrome or inflammation markers at ages approximately 32 years. The nature of the sample and lack of measurement of depressive disorder diagnosis tempers the conclusions, and future research is needed to determine associations with biological measures at later life span phases.",
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N2 - Objective Depressive symptoms and major depression predict cardiovascular disease (CVD) and CVD risk factors in adulthood. Evidence regarding the role of depression in the development of CVD risk in youth is minimal. The study evaluated the prospective relationship of depressive symptoms in childhood and adolescence with adult CVD risk factors in black and white men. Methods Health behaviors and medical history were measured in 165 black and 146 white men (mean age = 32); a subset in the Pittsburgh area had a fasting blood draw to measure metabolic syndrome and inflammation. Adult CVD risk factors were related to depressive symptoms and childhood socioeconomic status (SES) prospectively measured annually from ages 7 to 16 years, followed by adjustments for adult SES and depressive symptoms. Results Men with higher depressive symptoms ages 7 to 16 smoked more cigarettes, B = 0.28 (standard error = 0.12), p =.015, and ate fewer servings of fruits and vegetables, B = -0.08 (0.04), p =.040, as adults. The association for smoking was independent of adult depressive symptoms (concurrent) and childhood and adult SES as well as race. Depressive symptoms during childhood were unrelated to the metabolic syndrome or biomarkers of inflammation in adulthood. Conclusions Depressive symptoms in childhood may predict later adverse health behaviors in black and white men. No evidence was found for an association between childhood depressive symptoms with metabolic syndrome or inflammation markers at ages approximately 32 years. The nature of the sample and lack of measurement of depressive disorder diagnosis tempers the conclusions, and future research is needed to determine associations with biological measures at later life span phases.

AB - Objective Depressive symptoms and major depression predict cardiovascular disease (CVD) and CVD risk factors in adulthood. Evidence regarding the role of depression in the development of CVD risk in youth is minimal. The study evaluated the prospective relationship of depressive symptoms in childhood and adolescence with adult CVD risk factors in black and white men. Methods Health behaviors and medical history were measured in 165 black and 146 white men (mean age = 32); a subset in the Pittsburgh area had a fasting blood draw to measure metabolic syndrome and inflammation. Adult CVD risk factors were related to depressive symptoms and childhood socioeconomic status (SES) prospectively measured annually from ages 7 to 16 years, followed by adjustments for adult SES and depressive symptoms. Results Men with higher depressive symptoms ages 7 to 16 smoked more cigarettes, B = 0.28 (standard error = 0.12), p =.015, and ate fewer servings of fruits and vegetables, B = -0.08 (0.04), p =.040, as adults. The association for smoking was independent of adult depressive symptoms (concurrent) and childhood and adult SES as well as race. Depressive symptoms during childhood were unrelated to the metabolic syndrome or biomarkers of inflammation in adulthood. Conclusions Depressive symptoms in childhood may predict later adverse health behaviors in black and white men. No evidence was found for an association between childhood depressive symptoms with metabolic syndrome or inflammation markers at ages approximately 32 years. The nature of the sample and lack of measurement of depressive disorder diagnosis tempers the conclusions, and future research is needed to determine associations with biological measures at later life span phases.

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KW - cigarette smoking

KW - CRP = C-reactive protein

KW - CVD = cardiovascular disease

KW - DBP = diastolic blood pressure

KW - depression

KW - HDL-C = high density lipoprotein-cholesterol

KW - health behaviors

KW - IL-6 = interleukin 6

KW - inflammation

KW - longitudinal

KW - men

KW - metabolic syndrome

KW - PYS = Pittsburgh Youth Study

KW - race

KW - SBP = systolic blood pressure

KW - SES = socioeconomic status

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