Deduced amino acid sequence and potential O-glycosylation sites for the bovine coronavirus matrix protein.

W. Lapps, Brenda Hogue, D. A. Brian

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The nucleotide sequence of the matrix (M) protein gene of the bovine coronavirus (BCV) was determined by sequencing cDNA clones derived from genomic RNA. The gene was found to map at the 5' side of the nucleocapsid protein gene and its sequence predicts a protein of 230 amino acids having a molecular weight of 26,376. The BCV M protein shares extensive sequence homology with the matrix protein of the mouse hepatitis coronavirus (MHV) but differs notably in the amino terminal region external to the virion envelope where BCV apparently uses at least two of its six potential O-glycosylation sites.

Original languageEnglish (US)
Pages (from-to)123-129
Number of pages7
JournalAdvances in Experimental Medicine and Biology
Volume218
StatePublished - 1987
Externally publishedYes

Fingerprint

Bovine Coronavirus
Glycosylation
Amino Acid Sequence
Amino Acids
Genes
Nucleocapsid Proteins
Coronavirus
Proteins
Sequence Homology
Virion
Hepatitis
Nucleotides
Complementary DNA
Clone Cells
Molecular Weight
Molecular weight
RNA

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Deduced amino acid sequence and potential O-glycosylation sites for the bovine coronavirus matrix protein. / Lapps, W.; Hogue, Brenda; Brian, D. A.

In: Advances in Experimental Medicine and Biology, Vol. 218, 1987, p. 123-129.

Research output: Contribution to journalArticle

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