Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Gordon W. Harkins, Darren P. Martin, Siobian Duffy, Aderito L. Monjane, Dionne N. Shepherd, Oliver P. Windram, Betty E. Owor, Lara Donaldson, Tania van Antwerpen, Rizwan A. Sayed, Bradley Flett, Moses Ramusi, Edward P. Rybicki, Michel Peterschmitt, Arvind Varsani

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.

Original languageEnglish (US)
Pages (from-to)3066-3074
Number of pages9
JournalJournal of General Virology
Volume90
Issue number12
DOIs
StatePublished - 2009
Externally publishedYes

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Maize streak virus
Zea mays
Genetic Recombination
Food Supply
South Africa
Poaceae
Genome

ASJC Scopus subject areas

  • Virology

Cite this

Harkins, G. W., Martin, D. P., Duffy, S., Monjane, A. L., Shepherd, D. N., Windram, O. P., ... Varsani, A. (2009). Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. Journal of General Virology, 90(12), 3066-3074. https://doi.org/10.1099/vir.0.015537-0

Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. / Harkins, Gordon W.; Martin, Darren P.; Duffy, Siobian; Monjane, Aderito L.; Shepherd, Dionne N.; Windram, Oliver P.; Owor, Betty E.; Donaldson, Lara; van Antwerpen, Tania; Sayed, Rizwan A.; Flett, Bradley; Ramusi, Moses; Rybicki, Edward P.; Peterschmitt, Michel; Varsani, Arvind.

In: Journal of General Virology, Vol. 90, No. 12, 2009, p. 3066-3074.

Research output: Contribution to journalArticle

Harkins, GW, Martin, DP, Duffy, S, Monjane, AL, Shepherd, DN, Windram, OP, Owor, BE, Donaldson, L, van Antwerpen, T, Sayed, RA, Flett, B, Ramusi, M, Rybicki, EP, Peterschmitt, M & Varsani, A 2009, 'Dating the origins of the maize-adapted strain of maize streak virus, MSV-A', Journal of General Virology, vol. 90, no. 12, pp. 3066-3074. https://doi.org/10.1099/vir.0.015537-0
Harkins GW, Martin DP, Duffy S, Monjane AL, Shepherd DN, Windram OP et al. Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. Journal of General Virology. 2009;90(12):3066-3074. https://doi.org/10.1099/vir.0.015537-0
Harkins, Gordon W. ; Martin, Darren P. ; Duffy, Siobian ; Monjane, Aderito L. ; Shepherd, Dionne N. ; Windram, Oliver P. ; Owor, Betty E. ; Donaldson, Lara ; van Antwerpen, Tania ; Sayed, Rizwan A. ; Flett, Bradley ; Ramusi, Moses ; Rybicki, Edward P. ; Peterschmitt, Michel ; Varsani, Arvind. / Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. In: Journal of General Virology. 2009 ; Vol. 90, No. 12. pp. 3066-3074.
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