Dataset on the response of Hut78 cells to novel rexinoids

    Research output: Contribution to journalArticle

    Abstract

    This article presents the experimental data supporting analysis of differential gene expression of human cutaneous T cell lymphoma (CTCL) cell culture cells (Hut78) treated with bexarotene or a variety of rexinoids, in conjunction with “A Novel Gene Expression Analytics-based Approach to Structure Aided Design of Rexinoids for Development as Next-Generation Cancer Therapeutics” (Hanish et al. 2018). Data presented here include microarray gene expression analysis of a subset of genes. A novel method for analyzing gene expression in the context of a model of ligand mechanism, called the Divergence Score, is described. Analysis to identify the presence of potential retinoid response elements in putative promoter regions of the study genes is also presented.

    Original languageEnglish (US)
    Pages (from-to)1797-1803
    Number of pages7
    JournalData in Brief
    Volume20
    DOIs
    StatePublished - Oct 1 2018

    Fingerprint

    Gene Expression
    Cutaneous T-Cell Lymphoma
    Retinoids
    Response Elements
    Genetic Promoter Regions
    Genes
    Cell Culture Techniques
    Ligands
    Datasets
    Neoplasms
    Therapeutics
    bexarotene

    ASJC Scopus subject areas

    • General

    Cite this

    Dataset on the response of Hut78 cells to novel rexinoids. / Hackney Price, Jennifer; Hanish, Bentley J.; Wagner, Carl; Kaneko, Ichiro; Jurutka, Peter; Marshall, Pamela.

    In: Data in Brief, Vol. 20, 01.10.2018, p. 1797-1803.

    Research output: Contribution to journalArticle

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