Dataset on the response of Hut78 cells to novel rexinoids

Research output: Contribution to journalArticle

Abstract

This article presents the experimental data supporting analysis of differential gene expression of human cutaneous T cell lymphoma (CTCL) cell culture cells (Hut78) treated with bexarotene or a variety of rexinoids, in conjunction with “A Novel Gene Expression Analytics-based Approach to Structure Aided Design of Rexinoids for Development as Next-Generation Cancer Therapeutics” (Hanish et al. 2018). Data presented here include microarray gene expression analysis of a subset of genes. A novel method for analyzing gene expression in the context of a model of ligand mechanism, called the Divergence Score, is described. Analysis to identify the presence of potential retinoid response elements in putative promoter regions of the study genes is also presented.

Original languageEnglish (US)
Pages (from-to)1797-1803
Number of pages7
JournalData in Brief
Volume20
DOIs
StatePublished - Oct 1 2018

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Gene Expression
Cutaneous T-Cell Lymphoma
Retinoids
Response Elements
Genetic Promoter Regions
Genes
Cell Culture Techniques
Ligands
Datasets
Neoplasms
Therapeutics
bexarotene

ASJC Scopus subject areas

  • General

Cite this

Dataset on the response of Hut78 cells to novel rexinoids. / Hackney Price, Jennifer; Hanish, Bentley J.; Wagner, Carl; Kaneko, Ichiro; Jurutka, Peter; Marshall, Pamela.

In: Data in Brief, Vol. 20, 01.10.2018, p. 1797-1803.

Research output: Contribution to journalArticle

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