Cytotoxic naphthoquinones, molluscicidal saponins and flavonols from Diospyros zombensis

Frank Gafner, Jean Charles Chapuis, Jerome D. Msonthi, Kurt Hostettmann

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


7-Methyljuglone, isodiospyrin and three glucuronides of oleanolic acid were isolated from the lipophilic and the methanol extracts, respectively, of the root bark of Diospyros zombensis. Cytotoxic activities of the naphthoquinones and strong molluscicidal activity of 3-O-[O-α-L-rhamnopyranosyl-(1 → 3)-β-D-glucuronopyranosyl]-oleanolic acid were shown. In addition hyperoside, quercitrin and quercetin-3-O-β-D-glucuronopyranoside were isolated from a methanol extract of the leaves.

Original languageEnglish (US)
Pages (from-to)2501-2503
Number of pages3
Issue number9
StatePublished - 1987


  • Diospyros zombensis
  • Ebenaceae
  • cytotoxins.
  • flavone glycosides
  • molluscicides
  • naphthoquinones
  • saponins

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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