Cytokinins: Synthesis and growth-promoting activity of 2-substituted compounds in the N6-isopentenyladenine and zeatin series

Sidney M. Hecht, Nelson J. Leonard, Ruth Y. Schmitz, Folke Skoog

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Fourteen compounds were tested for relative promotion of cell division and growth (cytokinin) activity in the tobacco bioassay. The results suggested that 2-substituted-N6-(hydroxy)isopentenylaminopurines were generally less active than their unsubstituted couterparts. Thus, a 2-OH substituent greatly lowered cytokinin activity in both the isopentenyl and hydroxyisopentenyl (zeatin) series, while 2-NH2 and 2-SCH3 groups had a lesser effect on activity and a 2-Cl substituent had a negligible effect. Mass spectra were determined for all of the 9-β-d-ribofuranosides and for a number of the purines as well; the fragmentation patterns were consistent and characteristic, providing a possible systematic approach to the identification of new 2-substituted-N6-(hydroxy)isopentenyladenines.

Original languageEnglish (US)
Pages (from-to)1173-1180
Number of pages8
Issue number6
StatePublished - Jun 1970
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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