Cytokinins: Synthesis and growth-promoting activity of 2-substituted compounds in the N6-isopentenyladenine and zeatin series

Sidney Hecht, Nelson J. Leonard, Ruth Y. Schmitz, Folke Skoog

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Fourteen compounds were tested for relative promotion of cell division and growth (cytokinin) activity in the tobacco bioassay. The results suggested that 2-substituted-N6-(hydroxy)isopentenylaminopurines were generally less active than their unsubstituted couterparts. Thus, a 2-OH substituent greatly lowered cytokinin activity in both the isopentenyl and hydroxyisopentenyl (zeatin) series, while 2-NH2 and 2-SCH3 groups had a lesser effect on activity and a 2-Cl substituent had a negligible effect. Mass spectra were determined for all of the 9-β-d-ribofuranosides and for a number of the purines as well; the fragmentation patterns were consistent and characteristic, providing a possible systematic approach to the identification of new 2-substituted-N6-(hydroxy)isopentenyladenines.

Original languageEnglish (US)
Pages (from-to)1173-1180
Number of pages8
JournalPhytochemistry
Volume9
Issue number6
DOIs
StatePublished - 1970
Externally publishedYes

Fingerprint

Zeatin
Cytokinins
isopentenyladenine
zeatin
cytokinins
Purines
synthesis
Tobacco
Bioassay
purines
Biological Assay
Cell Division
cell division
cell growth
tobacco
bioassays
Cells
Growth
growth promoting activity
N(6)-(delta(2)-isopentenyl)adenine

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

Cytokinins : Synthesis and growth-promoting activity of 2-substituted compounds in the N6-isopentenyladenine and zeatin series. / Hecht, Sidney; Leonard, Nelson J.; Schmitz, Ruth Y.; Skoog, Folke.

In: Phytochemistry, Vol. 9, No. 6, 1970, p. 1173-1180.

Research output: Contribution to journalArticle

Hecht, Sidney ; Leonard, Nelson J. ; Schmitz, Ruth Y. ; Skoog, Folke. / Cytokinins : Synthesis and growth-promoting activity of 2-substituted compounds in the N6-isopentenyladenine and zeatin series. In: Phytochemistry. 1970 ; Vol. 9, No. 6. pp. 1173-1180.
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