Cytokinins: Synthesis and biological activity of zeatin esters and related compounds

Ruth Y. Schmitz, Folke Skoog, Sidney Hecht, Nelson J. Leonard

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The esters of the highly active cytokinin zeatin [6-(4-hydroxy-3-methyl-trans-2-butenylamino) purine] with formic, propionic, and indole-3-acetic acids and of its 2-chloro-substituted derivative [2-chloro-6-(4-hydroxy-3-methyl-trans-2-butenylamino)purine] with acetic and propionic acids have been synthesized, and their growth-promoting activities in the tobacco bioassay have been determined and compared with those of four known, related compounds: zeatin, 6-(4-acetoxy-3-methyl-trans-2-butenylamino)purine, methyl 2-methyl-4-(purin-6-ylamino)-trans-crotonate, and 2-chlorozeatin. The five new esters were fully as active as any cytokinins we have tested in the tobacco bioaassy. The three zeatin esters were consistently, although only slightly, more active than zeatin, and each of the 2-chlorozeatin esters showed activity about twice that of zeatin on a molar basis.

Original languageEnglish (US)
Pages (from-to)275-280
Number of pages6
JournalPhytochemistry
Volume10
Issue number2
DOIs
StatePublished - 1971
Externally publishedYes

Fingerprint

Zeatin
Cytokinins
zeatin
Bioactivity
cytokinins
bioactive properties
Esters
esters
purines
synthesis
Tobacco
Crotonates
tobacco
Bioassay
Propionates
propionic acid
Acetic Acid
Biological Assay
indole acetic acid
bioassays

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

Cytokinins : Synthesis and biological activity of zeatin esters and related compounds. / Schmitz, Ruth Y.; Skoog, Folke; Hecht, Sidney; Leonard, Nelson J.

In: Phytochemistry, Vol. 10, No. 2, 1971, p. 275-280.

Research output: Contribution to journalArticle

Schmitz, Ruth Y. ; Skoog, Folke ; Hecht, Sidney ; Leonard, Nelson J. / Cytokinins : Synthesis and biological activity of zeatin esters and related compounds. In: Phytochemistry. 1971 ; Vol. 10, No. 2. pp. 275-280.
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