@article{e9543f4a73514b1e824c8c1a18c59b00,
title = "Cytokinins: Synthesis and biological activity of zeatin esters and related compounds",
abstract = "The esters of the highly active cytokinin zeatin [6-(4-hydroxy-3-methyl-trans-2-butenylamino) purine] with formic, propionic, and indole-3-acetic acids and of its 2-chloro-substituted derivative [2-chloro-6-(4-hydroxy-3-methyl-trans-2-butenylamino)purine] with acetic and propionic acids have been synthesized, and their growth-promoting activities in the tobacco bioassay have been determined and compared with those of four known, related compounds: zeatin, 6-(4-acetoxy-3-methyl-trans-2-butenylamino)purine, methyl 2-methyl-4-(purin-6-ylamino)-trans-crotonate, and 2-chlorozeatin. The five new esters were fully as active as any cytokinins we have tested in the tobacco bioaassy. The three zeatin esters were consistently, although only slightly, more active than zeatin, and each of the 2-chlorozeatin esters showed activity about twice that of zeatin on a molar basis.",
author = "Schmitz, {Ruth Y.} and Folke Skoog and Hecht, {Sidney M.} and Leonard, {Nelson J.}",
note = "Funding Information: * Supported at the University of Illinois by a researchgrant (GM-05829) from the National Institutes of Health, U. S. Public Health Service, and at the University of Wisconsin by a research grant (GB-6994X) from the National Science Foundation and by the Research Committee of the Graduate School with funds from the Wisconsin Alumni Research Foundation. t National Institutes of Health Predoctoral Fellow, 1967-70. Present address: Laboratory of Molecular Biology, University of Wisconsin, Madison, Wisconsin, U.S.A. 1 N. J. LEONARDS, , M. HECHT,F . SK~~G and R. Y. SCHMITZ,P roc. Natl. Acud. Sci. U.S. 63,175( 1969). 2 S. M. HECHT,N . J. LEONARDR, . Y, SCHMITZa nd F. SKOOG,P hytochem9. ,1173(1970). 3 D. S. LETHAM,J . S. SHANNONa nd I. R. MCDONALD, Proc. Chem.S ot. 230 (1964). 4 G. SHAW and D. V. Wnso~, Proc. Chem.S ot. 231 (1964). s D. S. LETHAMJ, . S. SHANNONa nd I. R. C. MCDONALD, Tetrahedron3 ,479 (1967). 6 C. 0. MILLER,P roc. Natl. Acad. Sci. US. 47, 170( 1961). 275",
year = "1971",
month = feb,
doi = "10.1016/S0031-9422(00)94040-8",
language = "English (US)",
volume = "10",
pages = "275--280",
journal = "Phytochemistry",
issn = "0031-9422",
publisher = "Elsevier Limited",
number = "2",
}