Creating pathways towards aromatic building blocks and fine chemicals

Brian Thompson, Michael Machas, David Nielsen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Aromatic compounds represent a broad class of chemicals with a range of industrial applications, all of which are conventionally derived from petroleum feedstocks. However, owing to a diversity of available pathway precursors along with natural and engineered enzyme 'parts', microbial cell factories can be engineered to create alternative, renewable routes to many of the same aromatic products. Drawing from the latest tools and strategies in metabolic engineering and synthetic biology, such efforts are becoming an increasingly systematic practice, while continued efforts promise to open new doors to an ever-expanding range and diversity of renewable chemical and material products. This short review will highlight recent and notable achievements related for the microbial production of aromatic chemicals.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume36
DOIs
StatePublished - Dec 1 2015

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Synthetic Biology
Metabolic Engineering
Petroleum
Enzymes
Metabolic engineering
Aromatic compounds
Feedstocks
Industrial applications
Industrial plants
Crude oil

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Creating pathways towards aromatic building blocks and fine chemicals. / Thompson, Brian; Machas, Michael; Nielsen, David.

In: Current Opinion in Biotechnology, Vol. 36, 01.12.2015, p. 1-7.

Research output: Contribution to journalArticle

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